Canada's Michael Smith Genome Sciences Centre offers scientists, researchers and others the opportunity to pursue careers at the forefront of genome science and precision medicine. With close ties to local and national clinical and academic communities—and to scientific collaborators around the world—we offer a rich and diverse research environment. With offices and laboratories located in Vancouver, British Columbia, we work in a city that consistently ranks as one of the best places in the world to live.

Come work with us!

Our commitment to equity, diversity and inclusion

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

COVID-19

All jobs at the GSC are based in Vancouver, British Columbia, Canada. With current COVID-19 conditions and restrictions, for positions with work that can be conducted remotely, some employees and positions will be required to work remotely. Flexible work options may be extended for some positions in the future. Regardless, employees in most roles must be able to work onsite at the GSC, offsite (from home or remotely) or some combination of these.

HEU and HSA union members
Internal applicants please visit internaljobs.phsa.ca to apply online for internal job postings.

Quality Assurance Associate

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RPC-R00022-2021-05-07

BC Cancer has an opening for a full time Quality Assurance Associate. The Quality Assurance Associate will assist in the coordination and administration of the Quality Management System for the Cancer Immunotherapy Program at the BC Cancer's Deeley Research Centre (DRC) in Victoria, BC. This position can be based in Vancouver, B.C. or Victoria, B.C.

These duties include, but are not limited to, document control, nonconformance and corrective/preventative actions, instrument calibration/preventive maintenance, vendor management, material and equipment risk assessments, quality system training, compiling documentation for regulatory submissions and other activities as appropriate to maintain GMP compliance for the BC Cancer ‘s Cancer Immunotherapy Program.

The Quality Assurance Associate receives guidance from and reports to, BC Cancer's Cancer Immunotherapy Program's Quality Manager or delegate.

Key Accountabilities:

  • Maintaining and controlling documents and records, ensuring only current and active documents are used, and obsolete or superseded ones are archived appropriately.
  • Performing document control tasks such as documentation completeness verification and release of approved documents.
  • Assisting in developing and conducting quality related training sessions for manufacturing, research and quality staff. Maintaining training records for all staff.
  • Overseeing and maintaining a comprehensive nonconformance /corrective and preventive action program. Assisting with root-cause investigations associated with deviations and non-conformances, and recommending follow-up and or/corrective actions. Ensuring nonconformance’s are completed in a timely manner and coordinates approvals.
  • Performing and approving vendor qualifications, conducting vendor risk assessments, maintaining an approved vendors list, maintaining vendor files and coordinating with vendors to receive updated certifications and material/service information.
  • Reviewer for equipment installation qualifications, operation qualifications and performance qualifications.
  • Helps prepare documentation for regulatory submissions, as required by the Head of Regulatory and Quality.
  • Participates in Point of Care (POC) cell Manufacturing Network initiatives for the production of CLIC (Canadian Lead Immunotherapies in Cancer) CAR-T cells throughout Canada.  
  • Participating in internal and external audits as needed.
  • Performing other related duties as assigned.

Qualifications

Education, Training and Experience

  • A Bachelor's degree from a recognized university in Biology, Chemistry, Molecular Biology or a related discipline.
  • Minimum three (3) years of experience in Quality Management Systems with particular experience in the following processes:
    • vendor management,
    • risk assessments, and
    • nonconformance’s/corrective and preventive actions.
  • Standards and regulatory knowledge with GMP, FACT, ISO 13485, ISO 14971, FDA 21 CFR 820 and/or Health Canada’s Requirements.
  • Knowledge of the clinical trials regulatory environment in Canada, cell therapy, immunology, and/or immunotherapy would be an asset.

Skills and Abilities

  • Demonstrated ability to accept responsibility and work independently.
  • Demonstrated ability to work effectively with others in a team environment.
  • Demonstrated ability to organize work and establish priorities.
  • Demonstrated ability to communicate effectively both orally and in writing.
  • High attention to detail, excellent organizational and time management skills and clear, concise writing and proof-reading skills.
  • Proficiency in relevant software applications, such as Word and Excel. Knowledge and experience in document control software (e.g. QPulse) would be an asset.

Terms of Employment

  • May be required to work extended hours, weekends and holidays
  • May be required to travel between Vancouver and Victoria
  • May be required to perform work outside scope of responsibilities, as needed​

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

*We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

*All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on a temporary basis. This restriction would be re-evaluated upon re-contracting.

Client Support Analyst

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Summary

Job Reference No: CSA_HEU# 107599_F00420_2021_04_27

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

Provides computer technical support services at the Genome Sequence Centre (GSC).  Duties include investigating and resolving hardware and software problems, installing, configuring and testing hardware and software, providing training to users and participating in GSC bioinformatic projects.

Duties

  • Maintains the computer system and network for the GSC by performing duties such as responding to system, communications and user problems, investigating problems and taking corrective action as per established procedures. Resolves user issues on the technical infrastructure. Refers problems as required Installs, configures, modifies and tests all computer hardware within the GSC network.
  • Installs, configures and upgrades server software as directed.
  • Installs and provides technical support for GSC operating systems and including UNIX-based scientific applications such as Apache, AceDB, CONSED, MySQL, Perl Modules, and other bioinformatic software.
  • Provides training to users in the use of hardware and software and prepares instructional material.
  • Works with others in the implementation of the GSC network infrastructure (servers, network, workstations, website) by installing network components and testing.
  • Installs, configures, modifies and tests all computer hardware within the GSC network.
  • Maintains printers, barcode readers and associated hardware.
  • Modifies website content as required.  Maintains hardware and runs web server software.
  • Carries out and monitors GSC wide backup and recovery procedures.
  • Provides input into the development of the GSC’s information technology infrastructure strategy which includes data, voice and video technology.
  • Under direction, monitors and maintains security profiles for computer systems by adding and deleting user names and reviewing security logs.
  • Codes, modifies, tests and maintains programs from specifications to complement systems implementation and meet technical and client support requirements.
  • Maintains an inventory of software and their version for all computers within the GSC network.
  • Writes basic computer programs to automate frequently performed tasks.
  • Performing other related duties as required.

Qualifications

Education, Training and Experience

Completion of Grade 12 plus graduation from a recognized two (2) year systems technology diploma, plus two (2) years of recent related experience or an equivalent combination of education, training and experience.

Skills and Abilities

  • Ability to type.
  • Ability to communicate and deal effectively both verbally and in writing.
  • Ability to work with other effectively.
  • Physical ability to carry out the duties of the position.
  • Ability to organize work.
  • Ability to operate related equipment.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a temporary basis. This restriction would be re-evaluated upon re-contracting.

Computational Biologist, LIMS

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

 

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: CB LIMS HSA # 107100_P01067_2021_04_16

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority, patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist will participate in the analysis of sequencing data by developing, refining and adapting bioinformatics tools for a high-throughput processing pipeline.  The Computational Biologist will also participate in the development and maintenance of the production databases, which provide tracking of all of the laboratory and bioinformatics analysis pipelines at the GSC.  Additionally, the Computational Biologist will assist in the packaging and distribution of developed tools and analysis results to the scientific community, and will be contributing to the preparation of scientific publications. 

Duties

  • Assists in the development and maintains the core sequence analysis pipelines at GSC, including but not limited to:
    • QC of sequencing data;
    • Alignment of sequenced reads;
    • Formatting and manipulation of alignment files for use by downstream pipelines (e.g. merging, reheadering);
    • Dissemination of data to collaborators;
    • New analyses pipelines as required.
  • Assists in the development and maintains GSC laboratory, quality and analysis databases, including:
    • Routine database integrity checks and database maintenance;
    • Development of views and interfaces for data entry;
    • Development of reports for internal users and collaborators;
    • Investigation of new frameworks and designing new schemas and tables.
  • Communicates with stakeholders in the lab, on analysis teams, and with external collaborators to understand and document requirements for development and to respond to questions about collaborator data and data quality.
  • Works with upstream and lab teams generating data to be housed in the database, and with downstream users of the databases to meet requirements, and responds to internal requests for query and API support.
  • Participates in the development and maintains ETL pipelines between GSC production databases.
  • Manages the storage and compression of over 5Pb of internally generated sequencing data as well as the download and storage of external data.
  • Works closely with GSC Systems team and Quality Assurance team to establish and carry out best practices for data security, and ensure compliance with ISO 27001 certification, CAP/DAP clinical accreditation requirements and other data use agreements.
  • Tests and validates new data analysis software for analyses such as alignment, duplicate marking and merging.
  • Participates in code walk-throughs and reviews of solutions.
  • Participates in the design and builds database solutions, taking performance into consideration.
  • Coordinates production problem resolution for assigned applications, including working with other technical teams.
  • Produces thorough but concise written documentation of database tables, applications, validations, SOPs, and other processes and procedures as required.

Performs other related duties as required.

Eligibility

Education, Training and Experience

  • Graduation from a recognized Bachelor of Science Program in Computer Science or equivalent with significant computer science components. 
  • Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

  • Demonstrated expertise in database programming and database design.
  • Demonstrated ability in Python.
  • Experience designing and/or maintaining a relational database including knowledge of SQL or PostgreSQL, and with ORMs.
  • Experience with REST API development.
  • Experience with front-end web development (AngularJS, React).
  • Functional knowledge of distributed version control systems, such as GIT.
  • Experience developing software as part of a team, familiarity with Agile development and ticketing systems.
  • Comfortable working in an Unix environment, including experience with shell scripting and common command-line tools.
  • Excellent verbal and written communication skills.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.

Computational Biologist, Variant Databases

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: CBVD_HSA Req # 107052_P01069_2021_04_16

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority, patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist will participate in the ongoing design, implementation and maintenance of the full stack (database backend as well as API, web visualization and frontend) of the database applications, housing genomic and clinical research data. The Computational Biologist will also participate in several high-profile national data sharing efforts in which the databases play a central role.

Duties

  • Participates in maintaining, designing and developing the GSC analysis and variant databases, including:
    • Checking data integrity and loading new data into existing tables;
    • Working with external data sources for genomic and sample metadata;
    • Design and implementation of new schemas and tables to house new data types;
  • API and front-end web application development.
  • Works with upstream bioinformatics and lab teams generating data to be housed in the database and responding to internal requests for query and API support.
  • Collaborates with other sequencing sites in Canada and internationally to share data and define best practices for data sharing.
  • Works closely with GSC Systems team and Quality Assurance team to establish and carry out best practices for data security, and ensure compliance with ISO 27001 certification, CAP/DAP clinical accreditation requirements and other data use agreements.
  • Works with clinical and research teams to develop web interfaces and patient reports for use in the clinic and within the research community.
  • Performs literature searches, testing and validation of new data analysis software, prepares presentations at scientific conferences.
  • Participates in code walk-throughs and reviews of solutions.
  • Participates in the design and build of database and software solutions taking performance into consideration.
  • Coordinates production problem resolution for assigned applications, including working with other technical teams.
  • Evaluates third-party software and incorporates new systems into legacy systems.
  • Produces thorough but concise written documentation of software, validations, SOPs, and other processes and procedures as required.

Qualifications

Education, Training and Experience

  • Graduation from a recognized Bachelor of Science Program in Computer Science or equivalent with significant computer science components. 
  • Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders. 

Skills and Abilities

  • Demonstrated expertise in database programming and database design.
  • Demonstrated ability in Python and/or Javascript (NodeJS).
  • Experience designing and/or maintaining a relational database including knowledge of SQL or PostgreSQL, and with ORMs.
  • Familiarity with non-relational databases such as Hadoop or graph databases.
  • Experience with REST API development.
  • Experience with front-end web development (React, AngularJS).
  • Functional knowledge of distributed version control systems, such as GIT.
  • Experience developing software as part of a team, familiarity with Agile development and ticketing systems.
  • Comfortable working in a UNIX environment, including experience with shell scripting and common command-line tools.
  • Excellent verbal and written communication skills.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.

Research Assistant 2, Proteomics

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RA 2_R00004_2021_04_14

Working as part of the proteomics core facility, the individual will assist in the day-to-day operation of the core. This individual will operate and maintain the hardware and software present in the core facility. In addition, this individual will work together with the Facility Manager and users to plan, coordinate, conduct and report on assigned research projects. Key responsibilities of the individual will include communication with colleagues and collaborators for project planning and results dissemination, preparation of samples for proteomic and/or metabolomic analysis, as well as basic mass spectrometry data analysis.

Key accountabilities include:

  • Performs a variety of established technical procedures according to written protocols.
  • Performs experiments by following established laboratory procedures according to written protocols.
  • Records results, including computer data entry.
  • Provides input regarding modification of procedures as requested by the Department Head, Principal Investigator, or designate.
  • Maintains and stores cell lines and primary cultures.
  • Maintains and stores test materials and products.
  • Maintains inventory of laboratory supplies and equipment.
  • May demonstrate work methods or procedures to less experienced assistants as designated.

Additional responsibilities include:

  • Liaising with collaborators to coordinate sample submission
  • Preparing samples for proteomic analysis
  • Analyzing the samples on facility instrumentation
  • Operating and maintaining facility instrumentation
  • Performing initial mass spectrometry data analysis
  • Maintaining logs of samples analyzed and instrument use
  • Communicating results to lab members as well as collaborators

Eligibility

The successful candidate is expected to have a level of education, training, and experience equivalent to graduation from a recognized technical program in an appropriate discipline or similar; plus two (2) years of recent related experience in a research laboratory.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.

Knowledge Translation Coordinator

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Are you an excellent communicator with passion for science and technology?

Do you have a knack for creative writing and design, with an eye for detail?

Can you translate technical language and jargon for non-scientific audiences?

The GSC is looking to add a Knowledge Translation Coordinator to its Knowledge Translation team. Reporting to the Head of Knowledge Translation, this position will support the development of materials, activities and events that help communicate the GSC’s research projects, collaborations and innovations to a variety of audiences, both scientifically literate and not.

Main Responsibilities

  • Coordinate the development of digital and print materials as well as activities and events in collaboration with the Knowledge Translation team, scientists, trainees, project managers and other staff members.
  • Write, edit, design and proofread scientific and technical publications, as well as copy for non-scientific audiences including research summaries, web and social media content, multimedia, etc. 
  • Recommend strategies and develop plans, tools and practices for reaching new audiences in collaboration with the Head of KT and other project and program leaders.
  • Monitor status and progress for KT activities to ensure quality and timeliness; provides relevant information and project progress reports.
  • Propose and create compelling content (including design materials using Adobe Suite) for the web and social media related to the GSC’s research projects and programs, and technology platforms and services.
  • Identify and evaluate objectives and project milestones; flag discrepancies for the attention for the Head of KT.
  • Work with client relationship management software (Salesforce) to ensure timely and professional communications with stakeholders about research projects and scientific collaborations.

Qualifications

A level of education, training and experience equivalent to completion of a Bachelor’s of Science (a Master’s or PhD is an asset) in biology, genetics or a related field from a recognized university plus a minimum of five (5) years of recent related experience in an academic or industry research setting (experience in the biotechnology sector is an asset).

Skills and Knowledge

  • Demonstrated experience and expertise in science communication, including the development of plans and strategies, print and digital materials, and event organization, for research, education, business, marketing, promotion and/or knowledge translation/transfer/mobilization/exchange purposes.
  • Excellent command of the English language, and exceptional communications skills including in speech and writing; fluency with other languages is an asset.
  • Experience and confidence in editing, proofreading and/or providing review and critique on the written work of both junior and senior staff members, including scientists and principal investigators.
  • Understanding of Canadian scientific and research processes, including ethics, funding and peer-reviewed publication best practices.
  • Fundamental computer literacy is mandatory, including familiarity with the Microsoft suite of products (Word, Excel, PowerPoint, Outlook); experience with the Adobe Suite of products (Photoshop, Illustrator, InDesign) and/or with Client Relationship Management software (Salesforce) for business development purposes are very strong assets.
  • Demonstrated organizational, analytical and critical thinking skills, including the ability to manage multiple projects and activities within a fast-paced environment under pressure and to do so independently or cooperatively, optimistically and respectfully in a diverse and inclusive team environment.

Apply

Please submit a cover letter and resume to bcgscjobs@bcgsc.ca

The position will remain open until filled.

We thank all applicants; however, only those selected for the next step will be contacted.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority. 

Due to COVID-19 restrictions, the position will require working remotely on a temporary basis.

Research Assistant 2

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference Number: RA2-R0004-2021-03-10

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

Incumbents have directly related laboratory experience and familiarity with specific research programs and methodologies of the hiring laboratory.  They work under supervision and perform experiments by following established laboratory procedures.  They report to the Department Head, Principal Investigator, or designate, with duties including: 

  • Performs a variety of established technical procedures according to written protocols.
  • Performs experiments by following established laboratory procedures according to written protocols.
  • Records results, including computer data entry.
  • Provides input regarding modification of procedures as requested by the Department Head, Principal Investigator, or designate.
  • Maintains and stores cell lines and primary cultures.
  • Maintains and stores test materials and products.
  • Maintains inventory of laboratory supplies and equipment.
  • May demonstrate work methods or procedures to less experienced assistants as designated.

Eligibility

A level of education, training, and experience equivalent to graduation from a recognized Bachelor’s program in an appropriate discipline (e.g., Bachelor of Science) plus two (2) years of recent related experience in a research laboratory. A familiarity with mammalian cell culture techniques, flow cytometry/FACS and library construction for DNA sequencing will be considered essential assets.

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.

Post-Doctoral Fellow, Immunogenomics

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference Number: PDF-01553-2021-03-08

The GSC is seeking a Post-Doctoral Fellow to conduct scientific research in the areas of immunogenomics, T cell biology, and genetically engineered cell therapy, with a special focus on discovery and characterization of therapeutic T cell receptors using novel high-throughput screening approaches.

Experience in recombinant DNA and gene editing technologies, gene therapy vectors, mammalian cell culture (including primary T cell culture), flow cytometry/FACS, and cell-based assays (such as ELISPOT) is desired. Familiarity with 2nd and 3rd generation DNA sequencing platforms (including single-cell sequencing platforms) will be an asset.

Reporting to Dr. Robert Holt, Distinguished Scientist & Co-Director of the BC Cancer Immunotherapy Program, your typical duties will include the following:
•    Contributing to the design and construction of cell libraries for high-throughput screening experiments.
•    Performing high-throughput T cell receptor profiling screens.
•    Characterization and validation of novel discoveries stemming from high-throughput screening studies. 
•    Reporting research methods and results in meetings, seminars and conferences.
•    Contributing to and/or leading scientific publications and funding proposals

Eligibility

The ideal candidate should possess a PhD degree and recent experience in immunology, genomics, cancer biology, cell biology or a related discipline. A strong publication record and track record of successful funding applications are highly desirable. This position is funded by the Michael Smith Foundation for Health Research Innovation to Commercialization program and, as such, an interest or aptitude for technology development and/or industrial applications would be a valuable asset.  

Apply

Please submit a cover letter, curriculum vitae and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience and long-term career goals. Please email your application to bcgscjobs@bcgsc.ca.

Important!

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.

Project Manager

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC. But it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers and clinicians. We look for people who share our core values—science, timeliness and respect—to join us in our mission to provide genomics, bioinformatics and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity is essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.


Role Summary

The Genome Sciences Centre is seeking a Projects Manager. This role is for a Manager of research projects, grants and platforms in a research environment.

Reporting to the Head, Project Management or Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and monitor and facilitate progress against these objectives and milestones. Projects will involve personalized oncogenomics, collaborative services management, or other cancer genomics research.

Key Responsibilities

  • establishing budgets for research projects, grants, collaborations and core activities
  • assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
  • monitoring budgets and expenditures
  • establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives, which may include, meeting coordination and follow-up, coordination of case reviews
  • maintain accurate information on sample status, including sample and associated metadata acquisition, processing, stakeholder reporting
  • recommending strategies for improving projects management methods and processes
  • liaising with grant/core funding agencies
  • interacting directly with research collaborators or clinical study teamsas required

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged.

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will experience in academic scientific research, clinical trials research, the biotech or software industries. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at level Research Project Coordinator, which is equivalent to that described above.

To Apply

Please send a copy of your resume and a detailed cover letter to bcgscjobs@bcgsc.ca

Please note that this position will remain open until filled.

We thank all applicants; however, only those selected for the next step will be contacted.

Postdoctoral Fellow, Gastrointestinal Cancers

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.


Role Summary

A Post-doctoral position is available immediately for a highly motivated recent PhD or MD/PhD graduate to join a dynamic translational research group, headed by Dr. Isabella Tai, Associate Professor in the Division of Gastroenterology, University of British Columbia and Senior Scientist at Canada's Michael Smith Genome Sciences Centre at BC Cancer.

Current projects in the laboratory revolve around improving our understanding of the mechanisms involved in the development of chemotherapy resistance and metastasis in gastrointestinal cancers (colorectal, gastric, liver and biliary cancers). The goal is to develop either novel therapeutic targets for GI cancer treatment or novel screening tools for diagnosis. We continue to use the latest genomics (including single cell sequencing), proteomics and bioinformatic approaches to identify potential targets or markers for this purpose. Learn more about research projects in the Tai lab here.

Eligibility

Interested individuals with a recent PhD or MD/PhD and strong publication records and excellent academic credentials are encouraged to apply.  Experience in molecular biology, cell biology, tissue culture and animal tumor models, is preferable.  Experience in bioinformatics is an asset.

Duration

Three years (possibility of extension).

To Apply

Please submit a cover letter, curriculum vitae, and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience, long-term career goals and an indication of the desired length of postdoctoral position.

Please email your application to bcgscjobs@bcgsc.ca

Research Programmer

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.


Role Summary

The Karsan lab team at Canada’s Michael Smith Genome Sciences Centre (GSC) is seeking a research programmer to join a Genome British Columbia software automation project. The team will be working with the Karsan lab, which is responsible for developing high-throughput, clinically accredited pipelines to analyse sequenced data from genomic assays for individualized patient management of cancer. We seek candidates with strong Python software and programming skills to automate and improve existing pipelines and potentially incorporate third-party software into the system.

The role is ideally suited for a creative individual with a strong interest in software development and testing, data analysis, and automation within a high throughput academic setting.

Key responsibilities

  • Design, plan, and implement automated bioinformatics pipelines to meet the objectives of the project
  • Work with other project team members to develop and test code, and implement software
  • Evaluate third-party software and incorporate new systems into legacy systems
  • Produce thorough but concise written documentation of algorithms, validations, SOPs, and other processes and procedures as required

Qualifications

Education, training and experience

  • Graduation from a recognized Bachelor of Science Program in Computer Science. A Master’s degree in a relevant field would be a strong asset. 
  • Two (2) years of recent related experience or an equivalent combination of education, training, and experience acceptable to the project lead.

Core Skills and Abilities 

  • Expertise with Python 3.X and able to provide links to code samples via GitHub or another open repository
  • Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
  • Familiarity with molecular and cellular biology
  • Excellent verbal and written communication skills.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.

Additional Assets

  • Familiarity in statistical analysis using modern computational tools.  Experience with any relevant tools will be considered, but R and Python are preferred
  • Familiarity with the development, testing, and maintenance of relational databases
  • Familiarity in next-generation sequencing
  • Experience with software testing
  • Experience with Agile software practices
  • Functional knowledge of distributed version control systems, such as SVN or GIT

To Apply

Please email your cover letter and resume to bcgscjobs@bcgsc.ca

Please note that this position will remain posted until filled.

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