Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: GSCC_F00412_Purchasing_2023_09_18

Job Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA, and as such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Genome Sciences Centre Clerk performs a variety of clerical duties such as assisting with the preparation of reports, maintaining computerized databases, speaking with vendors, reconciling invoices and assisting with the receipt of goods and equipment.

Duties

1. Assists in the preparation of routine laboratory expenditure reports including monthly and annual reports by performing duties such as compiling information from a variety of sources, entering information into financial spreadsheet software such as Excel and producing reports for forwarding to the supervisor.
2. Updates laboratory inventory database by performing duties such as receiving inventory documents, checking for completeness, contacting vendors and entering data into computerized inventory system.
3. Places specific purchase orders with designated external suppliers by performing duties such as contacting suppliers, completing purchase order and arranging for approvals and forwarding to suppliers.
4. Obtains information such as prices and estimated delivery dates for supplies and/or equipment by performing duties such as using the Internet to identify sources and prices of supplies and/or equipment and forwarding information to supervisor.
5. Contacts external suppliers to investigate a variety of matters such as incorrect invoices, pricing problems, outstanding or backordered items and damaged goods; traces duplicate shipments and organizes invoice adjustments and credit notes with suppliers; returns outdated and/or deleted stock to vendors as directed.
6. Maintains a library of supplies and equipment catalogues by performing duties such as using the Internet to identify sources of catalogues, requesting current catalogues from suppliers, and providing information to staff as requested.
7. Reconciles designated accounts by performing duties such as matching information including payments received, refunds and invoices issued and identifying differences. Balances information with ledger. Refers problems to supervisor.
8. Performs a variety of duties related to the receiving of goods and equipment including unpacking, labelling and recording receipt of goods and equipment.
9. Maintains a variety of laboratory supplies and reagents by performing duties such as by performing duties such as reviewing stock on hand against pre-determined re-order points and completing requisitions for approval and forwarding to purchasing.
10. Maintains information such as MSDS sheets, product information and price lists by performing duties such as receiving and requesting information, advising staff of new and/or changed information and filing for future reference.
11. Performs other related duties as assigned.

Qualifications

Education, Training and Experience

• Grade 12 and two year's recent related experience or an equivalent combination of education, training and experience.

Skills and Abilities

• Ability to keyboard at 45 w.p.m.
• Ability to communicate effectively both verbally and in writing.
• Ability to deal with others effectively.
• Physical ability to carry out the duties of the position.
• Ability to supervise
• Ability to operate related equipment.
• Ability to organize work.

Application

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 152502.

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: GSCC_F00412_Purchasing_2023_09_18 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are onsite positions based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RA_R00006_Bioinformatics_2023_09_15

Role Summary

The Research Associate will collaborate closely with diverse teams to lead activities focused on the development, application, and validation of novel approaches and workflows within genomic technologies. This dynamic role plays a pivotal part in advancing the field of genomics and contributing to significant projects, including BC Cancer's Personalized OncoGenomics program and the TFRI-led Marathon of Hope Cancer Centres Network. —a major federal initiative co-developed with GSC involvement to accelerate the adoption of cancer precision medicine in Canada, as well as CGEn Technology Development.

Major Responsibilities

• Developing bioinformatics workflows for new projects that require quick turnarounds and/or reproducible results and, where relevant, containerizing them.
• Analyzing sequencing data from technology development experiments in the lab, summarizing results and formally presenting findings in meetings and discussions, including at local, national and international conferences as well as internal meetings.
• Supporting technological advances and providing recommendations to wet and dry lab production groups on new technology and workflow optimizations based on comparative analyses, often with custom bioinformatics tools and workflows.
• Facilitating the transfer of novel analysis pipelines and technologies into production, such as drafting Standard Operating Procedures, training production staff, and assisting with troubleshooting exercises.
• Contributing to grant applications, protocol preparation, and other funding-related documents.
• Performing other related duties as required.

Qualifications
Education and Experience:

• PhD in molecular genetics, molecular biology, genomics, bioinformatics or related field.
• Exploratory data analysis(EDA) involving Illumina and/or ONT data.
• Familiarity with whole genome, transcriptome, capture and epigenetic data.
• Programming experience is a must, preferably with experience in scripting (Python), statistical analysis and data visualisation (eg. R, Matplotlib).
• Familiarity with pipeline tools (eg. Nextflow, singularity) and high-performance computing (slurm) are highly desirable.
• Knowledge and experience with public sequence data repositories (SRA, EGA) are also assets.
• Excellent written and verbal communication skills to effectively convey complex scientific ideas.
• Strong organization skills with the ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_Bioinformatics_2023_09_15 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RA_R00006_POG_2023_09_14

Summary

The GSC is currently looking for a Research Associate to work on the Personalized OncoGenomics Program (POG). The goal of this program is to develop cutting-edge approaches to aid in the determination of relevant therapeutic options based on the genomic and transcriptomic information derived from a patient’s tumour. Working under the supervision of the Principal Investigator and the Group Leader, the successful incumbent will work with the project team to lead the activities on the development, implementation and performing bioinformatics analysis, as well as interpretation and communication of genomic data in a clinical context.

Duties include:

• Individualized in-depth analysis and interpretation of sequencing data from patient tumour whole genome and transcriptome analysis (WGTA) to evaluate cancer-associated pathways and identify potential clinically actionable targets.
• Communication of genomic findings to clinical teams in the form of written reports and oral presentations.
• Providing scientific direction, leading data analysis and preparation of manuscripts and/or presentation of research papers.
• Performing literature review and identifying, collecting and analyzing internal and external datasets.
• Testing and making use of software for inclusion into research projects.
• Assisting in the preparation of grants, protocols and other funding related documents.

Skills and Abilities:

• PhD in molecular genetics, molecular biology, genomics, bioinformatics or related field.
• Master’s degree in bioinformatics, human molecular genetics, genomics, oncology may be considered.
• Broad understanding of human molecular genetics and cancer biology.
• Experience working with human genomic data, specifically next generation sequencing data (WGS, RNAseq).
• Experience with a common programming languages (eg. Python or R).
• Excellent oral and written communication.
• Organization skills with the ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.'Ability to work in-person in the office located in Vancouver, BC, Canada.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_POG_2023_09_14 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. RP_R00008_VarDB_2023_08_25

Summary

The Software Developer to join the bioinformatics databases team at the Genome Sciences Centre (GSC) will work on developing databases and applications at the GSC, including the Hadoop-based VarDB, graphDB knowledgebase, and clinical databases. Strong Python and node.js server side application skills are required. The role is ideally suited for a creative individual with a strong interest in software development and testing, database development, and automation within a high throughput academic setting. General understanding of clinical or biological data would be an asset.

Duties/Accountabilities:

• Design, plan, and implement web applications and databases
• Work with other project team members to develop and test code, and implement software
• Evaluate third-party software and incorporate new systems into legacy systems
• Produce thorough but concise written documentation of algorithms, validations, SOPs, and other processes and procedures as required.

Qualifications:

• Graduation from a recognized Bachelor of Science Program in Computer Science. A Master’s degree in a relevant field would be a strong asset.
• Two (2) years of recent related experience or an equivalent combination of education, training and experience acceptable to the project lead.

Skills and Abilities:

• Functional knowledge of distributed version control systems, such as SVN or GIT
• Expertise with Python 3.X and able to provide links to code samples via github or other open repository
• Express.js, Node.js and React.js programming
• Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
• Familiarity with Agile software practices
• Familiarity with the development, testing, and maintenance of relational databases
• Experience with software testing
• Able to collaborate and write software in a team environment
• General biological scientific background or experience would be an asset
• Able to write in concise but precise prose
• Excellent verbal and written communication skills
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment
• Demonstrated ability to efficiently organize work assignments and establish priorities

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No. RP_R00008_VarDB_2023_08_25 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.  RA_R00006_Library Tech D_2023_08_24

Summary

The Research Associate will work within the Technology Development Group (Molecular Biology) under the direction of the Group Leader. Responsibilities include the evaluation of leading technologies that emerge in the marketplace, and the development of novel genomic technologies, such as those that support large-scale provincial and national projects, including BC Cancer’s Personalized OncoGenomics program, and the TFRI-led Marathon of Hope Cancer Centres Network—a major federal initiative co-developed with GSC involvement to accelerate the adoption of cancer precision medicine in Canada, as well as CGEn Technology Development. Tasks include assistance in testing, devising, developing and implementing omic technologies in the laboratory, as well as analyzing, proposing and presenting innovative workflows to increase the efficiency of genomics activities.

Responsibilities

• Test and/or develop novel and efficient methods to enable the scale and throughput the GSC requires to operate at the leading edge of its fields.
• Perform pilot or “custom” experiments, which may require e.g. following protocols published in the literature, or modifying an existing production protocol to meet specific project needs.
• Provide support to production groups, such as drafting Standard Operating Procedures, training production staff, and troubleshooting exercises.
• Summarize and analyze data and results, and formally present findings in meetings and discussions, including at local, national and international meetings. Interact closely and in support of group leaders and their teams to address priorities and project timelines 
• Co-author scientific manuscripts related to research and technology findings.
• Co-develop research grant applications.
• Contribute to quarterly and annual reports for research projects.
• Perform other related duties as required.

Qualifications

Education and Experience:

• PhD in a life sciences-related discipline, or MSc with 3 years demonstrated experience in genomics, or molecular biology. Knowledge or experience in e.g. high-throughput, large-scale DNA sequencing and genomic library production would be a plus.

Skills and Abilities:

• Molecular Biology.
• Knowledge and experience in laboratory automation.
• Knowledge of science and technologies pertaining to cancer genomics.
• Knowledge and experience in operating a laboratory information management system (LIMS) is advantageous.
• Experience with formal quality assurance systems is advantageous.
• Experience with high-throughput sequencing is desirable.

Experience in a supervisory role is an asset.  

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RA_R00006_Library Tech D_2023_08_24 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.  ABC_P00183_JR# 150051_CCGI_2023_08_08

Summary

Canada’s Michael Smith Genome Sciences Centre (GSC) of the BC Cancer Research Institute is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility in one of the most beautiful, diverse and eclectic cities in the world.

As an Assistant Bioinformatics Coordinator in the Clinical Panels Informatics team at the GSC, you will be responsible for supervising, coordinating and supporting activities related to clinical panel informatics through process monitoring, auditing and reporting as well as development, testing and validation of new clinical bioinformatics processes. The Assistant Bioinformatics Coordinator will report to the Bioinformatics Coordinator and is anchored within a team of exceptional computational scientists and programmers, who collaborate directly on the development and maintenance of robust, cost efficient, and competitive clinical genomics pipelines. By working within the GSCs bioinformatics facility, you will collaborate with clinical and research computational biologists and programmers across bioinformatics groups, clinical lab staff and the quality assurance group to deliver clinical diagnostic genomic testing for patients in BC.

Duties and Responsibilities:

1. Assists the Bioinformatics Coordinator in the day to day activities of the Bioinformatics group by performing duties such as providing input on quantity and quality of work, making recommendations for improvements, workflow and procedures.
2. Coordinates projects of the Bioinformatics group by performing duties such as chairing project-specific meetings and provides project status reports to the Bioinformatics Coordinator, with suggestions towards any required improvement of project management, task allocation and overall process.
3. Develops and implements assays to monitor project progress and measure project accomplishments to ensure that appropriate project focus is maintained and to provide feedback to staff.
4. Provides supervisory support to the Bioinformatics group by performing duties such as:

         a.   Orientating new staff.

         b.   Providing input to the Bioinformatics Coordinator on training requirements.

         c.   Providing input to the Bioinformatics Coordinator on the establishment of clear definitions of responsibility for employees.

         d.   Assigning workload assignments and establishing work schedules.

         e.   Reviewing and establishing work priorities and adjusting work schedules to ensure clinical priorities are met.

         f.    Completing performance reviews and addressing performance issues in conjunction with the Bioinformatics Coordinator.

5.         Participates in the recruitment of staff through methods such as interviewing internal and external applicants and forwards hiring recommendations.

6.         Participates in the implementation of quality improvement programs to ensure clinical assays are provided in the most efficient and effective way by performing duties such as:

         a.         Monitoring quality and quantity of service and information provided by the bioinformatics group and identifying areas for change and/or improvement.

         b.         Generating quality metrics and reports to evaluate quality and robustness of clinical bioinformatic pipelines

         c.      Develops clear and concise documentation

7.         Assesses practical needs for identified clinical priorities for GSC in conjunction with the Bioinformatics Coordinator and Analysis Group Leader.

8.         Participates in a variety of meetings by performing duties such as providing and/or receiving information and contributing to decision making.

9.         Participates, in conjunction with the Bioinformatics Coordinator, in determining the computer infrastructure necessary for successful completion of projects and ensured viability of research programs by performing duties such as providing input and recommendations regarding purchasing decisions related to hardware, software and related items for the clinical bioinformatics platform.

10.       Interprets statistical analyses and makes recommendations for review including preparing reports on statistical findings for publication and presentation both internally and externally of the GSC.

11.       Generates specification for pipeline improvements/implementations such as determining user requirements, examining and identifying problems with existing systems and recommending modifications to and/or new systems; provides details of cost benefit analysis

12.       Performs technical functions related to the bioinformatic functions of the GSC.

13.       Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor’s program in a related discipline such as Biochemistry, Genetics, Computer Science.  A minimum of four (4) years of recent related experience in a research and or clinical laboratory including experience in computer programming and quantitative data analysis, handling next generation sequencing data, database development and data storage schemas or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
• Proven expertise with Python, R, and/or other similar high-level languages
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated experience with analysis of next generation sequencing data with an understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
• Demonstrated ability to accept responsibility and work independently.
• Demonstrated ability to work effectively with others in a team environment.
• Demonstrated ability to supervise staff and to efficiently organize work assignments and establish priorities to meet set milestones.
• Excellent organizational, leadership interpersonal and communication skills.
• Demonstrated ability to write technical documents including validations and procedure manuals.
• Experience with bioinformatics workflow managers and database development would be considered an asset.
• Physical ability to perform the duties of the job.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using ABC_P00183_JR# 150051_CCGI_2023_08_08 in the subject line of your email.

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 150051.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RP_R00008_CCGI_2023_08_08

Summary

Canada’s Michael Smith Genome Sciences Centre (GSC) of the BC Cancer Research Institute is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility in one of the most beautiful, diverse and eclectic cities in the world.

As a Research Programmer within the Centre for Clinical Genomics Informatics team at the GSC, you will be responsible for technical support for clinical programs through development, testing and validation of clinical bioinformatics processes. The Research Programmer will report to the Process Development Coordinator and is anchored within a team of exceptional computational scientists and programmers, who collaborate directly on the development and maintenance of robust, cost efficient, and competitive clinical genomics pipelines. By working within the GSCs bioinformatics facility, you will collaborate with clinical and research computational biologists and programmers across bioinformatics groups, clinical lab staff and the quality assurance group to deliver clinical diagnostic genomic testing for patients in BC.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

So, what are you waiting for? Apply now!

Duties and Responsibilities:

• Works with team members to identify and implement pipeline improvements to optimize existing clinical pipelines.
• Works with stakeholders to design, plan and implement testing and development of new clinical bioinformatics software.
• Development and maintenance of clinical genomic databases.
• Delivery of clear and concise documentation.
• Actively participate in a team-oriented approach to improve efficiency and productivity.

Qualifications

• Graduation from a recognized Bachelor’s program in an appropriate discipline such as Computer Science, Bioinformatics, Genetics, Molecular Biology or Biochemistry, and three years of recent, related experience in a research and or clinical laboratory.
• Proven expertise with Python, R, and/or other similar high-level languages.
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated experience with analysis of next generation sequencing data with an understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
• Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
• Demonstrated ability to efficiently organize work assignments and establish priorities to meet set milestones.
• Demonstrated ability to write technical documents including validations and procedure manuals.
• Experience with bioinformatic workflow managers and database development would be considered an asset.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RP_R00008_CCGI_2023_08_08 in the subject line of your email.

This posting will remain online until filled.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.   RA_R00006_POG_2023_06_23

Summary

The GSC is currently looking for a Research Associate to work on the Personalized OncoGenomics Program (POG). The goal of this program is to develop cutting-edge approaches to aid in the determination of relevant therapeutic options based on the genomic and transcriptomic information derived from a patient’s tumour. Working under the supervision of the Principal Investigator and the Group Leader, the successful incumbent will work with the project team to lead the activities on the development, implementation and performing bioinformatics analysis, as well as interpretation and communication of genomic data in a clinical context.

Duties include:

• Individualized analysis and interpretation of patient tumour sequencing data to evaluate cancer-associated pathways and identify potential clinically actionable targets.
• Communication of genomic findings to clinical teams in the form of written reports and oral presentations.
• Providing scientific direction, leading data analysis and preparation of manuscripts and/or presentation of research papers.
• Performing literature review and identifying, collecting and analyzing internal and external datasets.
• Testing and making use of software for inclusion into research projects.
• Assisting in the preparation of grants, protocols and other funding related documents.

Skills and Abilities:

• PhD in molecular genetics, molecular biology, genomics, bioinformatics or related field.
• Broad understanding of human molecular genetics and cancer biology.
• Experience working with human genomic data, particularly next generation sequencing data (WGS, RNAseq).
• Experience with a common programming language (eg. Python or R).
• Excellent oral and written communication
• Organization skills with the ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_POG_2023_06_23 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference Number: RP_R0008_Steif Lab_2023_02_23

We are looking for an outstanding research programmer with experience developing and applying computational workflows for high-throughput sequencing data analysis to join Dr. Adi Steif’s cancer genomics research group in Vancouver, Canada.

The successful applicant will be part of an exceptional multidisciplinary team of bioinformatic scientists and trainees, working alongside collaborators in biomedical engineering and molecular biology at the University of British Columbia. By joining the Steif Lab, you will help advance genomic technology alongside highly motivated specialists in a creative and dynamic environment. You will have access to robust high performance computing infrastructure and unique and complex single cell sequencing datasets, all while living in one of the most beautiful, diverse and eclectic cities in the world.

We offer a competitive salary, excellent benefits and significant career development opportunities.

Responsibilities

Working in a multidisciplinary team, the research programmer will develop and maintain analytical workflows for high-throughput cancer genomics. This is a one-year term appointment, with potential for renewal. Responsibilities include:

• Design and implement robust computational workflows
• Thoroughly test and maintain high-quality, well-documented code
• Regularly review the scientific literature to ensure analysis is in line with best practices
• Contribute to data preprocessing and quality control
• Develop data visualizations and contribute to biological analysis and interpretation
• Regularly update Dr. Steif, group members and collaborators on the status of projects
• Participate in and present research updates at lab meetings and team meetings
• Contribute to scientific writing, including the preparation of research manuscripts and grant applications
• May be involved in the management and supervision of trainees

Qualifications

• A B.Sc. or M.Sc. in bioinformatics, computer science, statistics or related discipline
• At least 3 years of experience in bioinformatics
• Experience in genomics and high-throughput sequencing data analysis
• Experience in cancer research is an asset
• Programming fluency in Python or R
• Experience working in a Unix/Linux computing environment
• Critical thinking and attention to detail
• Excellent verbal, written and interpersonal communication skills
• Ability to work independently and in a collaborative interdisciplinary team
• A strong work ethic, with demonstrated ability to manage time and prioritize to meet deadlines

Application

Applicants should submit: a CV; a one-page cover letter explaining how your research experience, interests and career goals align with the position; and the names and contact details of three references to bcgscjobs@bcgsc.ca, using Job Reference No: RP_R0008_Steif Lab_2023_02_23 in the subject line of your email.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options are available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: CB_HSA# 147944_P01060_CCG_2023_06_23

Summary

In accordance with the Mission, Vision and Values, and strategic directions of Provincial Health Services Authority patient safety is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist performs bioinformatics analyses and contributes to software development related to the operation of a large-scale clinical sequencing facility. This is a temporary renewable full-time position

Duties

• Contributes to the design, development, implementation, validation, running, and maintenance of clinical bioinformatics pipelines and related databases.
• Contributes to incorporation of third-party software into clinical bioinformatics pipelines, including:
  1. identifying candidate software to consider
  2. comparing software candidates to aid in selection
  3. determining optimal parameters for the chosen software
  4. developing interfaces to integrate the chosen software and
  5. validating integration of the chosen software
• Participates in the development of novel software solutions, as directed by the Assistant Bioinformatics Coordinator or Clinical Bioinformatics Coordinator.
• Participates in peer code review.
• Contributes to writing and updating official procedures and other documentation related to clinical bioinformatics pipelines.
• Verifies results produced by clinical bioinformatics pipelines.
• Performs exploratory analyses to identify potential root causes of issues encountered during production processing, and implements corrective actions as directed by the Assistant Bioinformatics Coordinator or Clinical Bioinformatics Coordinator.
• Performs bioinformatics analyses to answer questions from the Clinical Director, Clinical Bioinformatics Coordinator, or Assistant Bioinformatics Coordinator.
• Presents implementation plans, analysis results, and validation results internally and externally, in oral presentations and written documentation.
• Contributes to the development of research papers by providing materials, methods, and/or analyzed data.
• Participates in the training of others through orientation, informal instruction, and sharing of job information.
• Performs other related duties as required.

Qualifications

Education, Training and Experience

• Graduation from a recognized Bachelor of Applied Science or Bachelor of Science Program in either Biological Sciences or Computer Science.
• Two (2) year’s of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

• Demonstrated skill with Python or other similar high level languages
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated ability in R or other similar statistical programming languages
• Familiarity with relational databases, such as PostgreSQL, and with ORMs
• Ability to program and run analyses in a production environment
• Excellent verbal and written communication skills
• Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment
• Demonstrated ability to efficiently organize work assignments to complete required tasks on time
• Familiarity with next-generation sequencing, cancer genetics, principles of clinical testing, experimental design, statistical hypothesis testing, and/or machine learning would be considered an asset
• Ability to use related equipment

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using  Job Reference: CB_HSA # 147944_P01060_CCG_2023_06_23 in the subject line of your email.

As this is a union position, you will also have to apply either as an internal or external applicant through http://www.phsa.ca/careers using the posting reference 147944.

While we value and review all applications, please note that due to the volume of submissions only shortlisted candidates will be contacted. This posting will remain online until the position is filled.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: RPC_R00022_Projects_2023_07_18

Summary

Reporting to Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and monitor and facilitate progress against these objectives and milestones.

Duties/Accountabilities

• Establishing budgets for research projects, grants, collaborations and core activities
• Assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
• Monitoring budgets and expenditures
• Establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives
• Recommending strategies for improving projects management methods and processes
• Liaising with grant/core funding agencies
• Interacting directly with research collaborators or clinical study teams as required
• Performing other related duties as appropriate

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will experience in academic scientific research, clinical trials research, biotech or software industry. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at the Research Project Coordinator level, which is equivalent to that described above.

Core Skills and Abilities

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RPC_R00022_Projects_2023_07_18 in the subject line of your email.

This posting will remain online until filled.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

PHSA and BC Cancer are committed to employment equity, encouraging all qualified individuals to apply. We recognize that our ability to provide the best care for our diverse patient populations relies on a rich diversity of skills, knowledge, background and experience, and value a safe, inclusive and welcoming environment.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No.; RA_R00006_Jones Lab_2023_07_24

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. We are currently looking for a Research Associate to work on the Genome Canada funded LSARP, “Canada’s Earth BioGenome project”. 

The successful incumbent will work with the project team to lead the activities on the development, application and validation of novel approaches and workflows in the area of integrated de novo genome assembly over multiple sequencing technologies. They will develop automated bioinformatics workflow as well as assembly submission. They will also work closely together with Earth BioGenome Project (EBP) consortium on the sequencing and assembly standards. They will work with Project Leaders to ensure all scientific milestones are achieved and contribute to progress reporting as required. There will be expectations to represent the project within the global EBP consortium and the development of outreach materials and website information. Opportunities will exist for further research on the genomic information developed and for scholarly publication.​

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on improving genome sequencing technology, interpretation and application. By working within Dr. Steven Jones' lab at the GSC , you will develop close relationships with world-renown specialists in bioinformatics and have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. 

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. Apply now!

Duties

• Work with multidisciplinary scientists at the GSC and collaborators to analyze whole genome and transcriptome sequence data and set up collaborative working plans.
• Develop and maintain bioinformatic pipelines for genome assembly and data analysis.
• Produce written documentation of algorithms, validations, SOPs and other processes related to pipeline updates and procedures as required.
• Present results of bioinformatics software testing internally and externally.
• Perform literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.
• Perform other related duties as required.

Qualifications

• Expertise in bioinformatics, emphasizing genome sequence analysis and gene annotation.
• Knowledge and experience using scientific tools, technologies and online resources as pertaining to de novo genome assembly.
• Fluency in multiple programming languages, including Python, Javascript and SQL.
• Expertise developing and operating in a UNIX/Linus environment and writing shell scripts.
• Experience developing custom scripts and pipelines using high performance computing and other available tools. Pipelines may include de novo assembly, annotation, database query, pan-genome construction and visualization tools, RNA-seq and phylogenetic tree reconstruction.
• Previous API development projects using Open API or Rest API is a plus.
• Excellent communication and organization skills, and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
• Ability for critical thinking and independent learning.
• Experience in a supervisory role is an asset.  

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_Jones Lab_2023_07_24 in the subject line of your email.

This position will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

Important!

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

Please note all jobs at the GSC are based in Vancouver, British Columbia, Canada. Flexible work options may be available for this position upon request and is subject to change in accordance with GSC’s operational needs and PHSA’s Flexible Work Options Policy.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

 

Job Reference No: RPC2_R00026_2021_07_06

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a Bachelor's degree in Health Information Science or Computer Science—along with experience in software/system project planning, analysis and implementation—this is your opportunity to join our team as a Business Analyst providing support for cutting-edge technology projects!

Reporting to the Head of Quality and Regulatory Affairs, the Business Analyst and Project Support (BA) leads the analysis and documentation of business requirements to support projects for designated programs and services. The successful candidate for this position will work in close collaboration with other stakeholders to develop business systems enhancements, business solutions, or business processes including GSC’s bioinformatics processes. The BA functions as a Subject Matter Expert to the project team through performing gap analysis of systems and business process mapping including the identification of linkages to other business systems.  

The BA position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs bioinformatics facility, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

Apply now! 

Duties and Responsibilities

• Provide key contributions to the development of solutions to ensure that business processes and/or project deliverables are consistent, accurate and timely.  
• Participate in and contribute to strategic planning. 
• Develop project plans for the design, development and implementation of new business processes; support the transition from current systems, practices and processes to an integrated system, common practices and standardized processes with current or improved functionality.  
• Ensure key results are achieved in accordance with the project plan by analyzing current business systems and processes, generating ideas and formulating recommendations/options, and supporting members of the project in prioritizing tasks and reaching decisions that are within project scope and timelines. 
• Implement or contribute to the implementation of effective processes to assess project risks, identify risk mitigation strategies and monitor risk throughout the project lifecycle. Support the Managers/Team Leads by providing regular updates on the progress as well as any areas of risk associated with the completion of the project both within the project scope and the timeline. Provide professional expertise to staff, departments, stakeholders, and guidance regarding standard process for project management.
• Coordinate and participate in the analysis, acceptance criteria definition, development, testing, training, implementation and maintenance phases of assigned bioinformatics projects. Carry out post-implementation reviews of systems and make recommendations for improvements.
• Utilize formal data gathering techniques and analysis tools such as flowcharts, diagrams, dashboards, roles and responsibility matrix (RACI) and work effort estimates. Provide details of estimated implementation costs including associated staffing requirements.
• Review, analyze and define current/future state processes, determine user and/or department requirements and contribute to the development of specifications and testing for all identified development, system modifications and installations. Perform impact analyses. 
• Provide user support, advice, guidance and orientation in situations that require interpretation and judgement. Develop content, as required, for training modules; deliver training and provide guidance to system users and department staff. Develop and maintain various business processes, policies and procedures, as well as reference documentation such as user instructions, manuals and reference materials.  
• Provide support to colleagues and users during the development, maintenance and operation of various computer systems by performing duties such as troubleshooting system software problems and testing alternative solutions. 
• Participate in the formal data collection and analysis to help identify system deficiencies and/or operational inefficiencies in order to report and develop new ways of improving business efficiencies including the data analysis related to business case developments, project proposals and other key strategic and transformative initiatives. 
• Assemble, create and maintain information systems technical and operational documentation according to departmental standards.
• Assist with preparation of Requests for Information/Proposal, development of evaluation processes and tools, and evaluation of vendor responses by serving on working groups, documenting detailed requirements and coordinating project team and vendor communications.

Qualifications

• A level of education, training and experience equivalent to a Bachelor's degree in Health Information Science, Computer Science or a related discipline—OR relevant related experience that includes software/system project planning, analysis and implementation.  
• Demonstrated ability to carry out business process mapping and fit gap analysis.  
• Excellent interpersonal, oral and written communication skills with the ability manage multiple interactions with multiple groups while working on multiple issues at the same time.  
• Superior analytical, problem-solving and system analysis skills.  
• Proven ability to plan and execute projects with stringent timelines.  
• Ability to work effectively as part of a team.  
• Demonstrated ability to provide professional expertise to staff, departments and stakeholders, and guidance regarding standard processes for software/computer system related project management.  
• Demonstrated ability to provide user support, advice and training, and other user liaison services.
• Public Service and Health Sector experience and knowledge are an asset.  

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Business Analyst and Project Support in the subject line of your email. 

This posting will remain open until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. 

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

JOB ID: PDC_E00375_Clinical_2021_08_11

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you are a computational scientist with clinical laboratory experience, who has designed and performed computational experiments that generate clinically relevant results, who understands and can improve upon process development and programming workflows, and is motivated to contribute towards scientific endeavours with real benefits to improve the lives of cancer patients—then join us!

As a Process Development Coordinator within the Clinical Bioinformatics Analysis team at the GSC, reporting to the Bioinformatics Group Leader, you will be responsible for leading the development, testing and validation of clinical bioinformatics processes. The PDC will develop new clinical procedures and bioinformatic workflows, monitor and review performance within the clinical production process, and where applicable, improve existing analyses; monitor results and compare them to best-practice standards; and always strives to streamline efficiency, maximize quality and balance cost. The PDC collaborates closely with key stakeholders for the clinical processes including the clinical director, bioinformatics groups and quality assurance group. You will need to be prepared to take initiative, to think critically and solve complex problems, to build and nurture collaborative relationships across departments, and to learn continuously.

The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient, and competitive processes for new targeted and precision medicine analytical pipelines. By working within the GSCs bioinformatics facility, you will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world. Your work will help to save lives and contribute to a world free from the fear of cancer.

This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.

So, what are you waiting for? Apply now!

Duties and Responsibilities

Oversees the development and testing of clinical bioinformatics production processes by:

• Designing and performing experiments pertaining to the generation of clinically relevant results.  This includes, but is not limited to, the development and testing of new analyses, protocol optimization, Quality Assurance and Quality Control, testing of prototypes and related activities. The PDC continually monitors performance of protocols within the production process and identifies areas for improvement. All activities will yield documented recommendations and implementation plans.
• Troubleshooting existing clinical computational processes where necessary. Makes recommendations and adjustments and reports problems.
• Training designated members of the clinical bioinformatics group in new or optimized analysis workflows. Writes or revises protocols accordingly.
• Performing technical functions related to the Bioinformatics groups of the GSC.

Qualifications

• Graduation from a recognized Bachelor’s program in an appropriate discipline such as Computer Science, Bioinformatics, Genetics, Molecular Biology or Biochemistry—OR an acceptable equivalent combination of education, training and experience.
• Proven expertise with Python and/or other similar high level languages.
• Demonstrated ability in R or other similar statistical programming languages and in statistical analysis.
• Functional knowledge of distributed version control systems, such as Git.
• Demonstrated experience with next generation/ third generation sequencing technology with an in-depth understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
• Excellent verbal and written communication skills.
• Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
• Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
• Experience liaising with multiple stakeholders to support consensus goals.
• Demonstrated ability to efficiently organize work assignments and establish priorities to meet set milestones.
• Demonstrated ability to write technical documents including validations and procedure manuals.
• Excellent analytical skills.
• Demonstrated ability to accept responsibility and work independently.
• Experience with bioinformatic workflow managers, e.g., Nextflow, would be considered an asset.
• Management experience is also an asset.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using the Job Reference No. PDC_E00375_Clinical_2021_08_11 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working on a hybrid basis, both remotely and onsite within British Columbia on a temporary basis. This restriction would be re-evaluated after finalization of full reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values — science, timeliness, respect — to join us on our mission to use genome science for the betterment of health and society.