Canada's Michael Smith Genome Sciences Centre offers scientists, researchers and others the opportunity to pursue careers at the forefront of genome science and precision medicine. With close ties to local and national clinical and academic communities—and to scientific collaborators around the world—we offer a rich and diverse research environment. With offices and laboratories located in Vancouver, British Columbia, we work in a city that consistently ranks as one of the best places in the world to live.

Come work with us!

Our commitment to equity, diversity and inclusion

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

COVID-19

All jobs at the GSC are based in Vancouver, British Columbia, Canada. With current COVID-19 conditions and restrictions, for positions with work that can be conducted remotely, some employees and positions will be required to work remotely. Flexible work options may be extended for some positions in the future. Regardless, employees in most roles must be able to work onsite at the GSC, offsite (from home or remotely) or some combination of these.

HEU and HSA union members
Internal applicants please visit internaljobs.phsa.ca to apply online for internal job postings.

Computational Biologist - Software Development, GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.: CBSD_P01066_HSA101465_2022_01_21

Summary

In accordance with the Mission, Vision and Values, and strategic directions of PHSA, safety, including both patient and employee safety, is a priority and a responsibility shared by everyone at PHSA. As such, the requirement to continuously improve quality and safety is inherent in all aspects of this position.

The Computational Biologist participates in developing, improving and maintaining bioinformatics tools for high-throughput processing pipelines. The Computational Biologist specifies, implements, tests and maintains bioinformatics computer applications and systems, and participates in the code walk-throughs and design and review of bioinformatics software solutions. The Computational Biologist will also assist in the packaging and distribution of developed tools and analysis results to the scientific community, and will contribute to the preparation of scientific publications.

Duties

  • Codes in Python and specifies, implements, tests, and maintains bioinformatics pipelines and applications as assigned.
  • Assists with devising or modifying systems to solve complex problems associated with high throughput pipelines, considering computer equipment capacity and limitations, operating time and form of desired results.
  • Participates in code walk-throughs and reviews of the coded solutions to PEP8 standards.
  • Participates in the design and build of database and software solutions taking performance into consideration.
  • Coordinates production problem resolution for assigned applications, including working with other technical teams.
  • Evaluates third-party software and incorporates new systems into legacy systems.
  • Produces written documentation of algorithms, validations, SOPs, and other processes related to pipeline updates and procedures as required.
  • Presents results of bioinformatics software testing internally and externally.
  • Performs literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.

Performs other related duties as required.

Qualifications

Education, Training and Experience

  • Graduation from a recognized Bachelor of Applied Science or Bachelor of Science Program in either Computer Science, Biological Sciences, or equivalent program.
  • Two (2) years of recent related experience in a bioinformatic setting or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and Abilities

  • Demonstrated expertise with Python or other similar high level languages for application in data analysis.
  • Demonstrated ability to program and run analysis in a high throughput bioinformatics production environment.
  • Functional knowledge of distributed version control systems, such as GIT.
  • Functional knowledge of Agile development and ticketing systems.
  • Demonstrated ability to work with bioinformatics workflow managers (e.g. Nextflow).
  • Excellent verbal and written communication skills.
  • Demonstrated ability to work in an Unix environment, including experience with shell scripting and common command-line tools.
  • Demonstrated ability to develop software as part of a team.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: CBSD_P01066_HSA101465_2022_01_21 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely on a temporary basis. This restriction would be re-evaluated upon re-contracting.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Postdoctoral Fellow - Sadar Lab

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: PDF_01553_Sadar Lab_2021_12_24

Summary

The laboratory of Dr. Marianne Sadar located within the Genome Sciences Centre within the BC Cancer Research Centre, in Vancouver, British Columbia, Canada has an opening for a post-doctoral fellow to work on a project involving application of novel antagonists of androgen receptor as imaging agents and therapeutics. The Sadar lab mainly focuses on the development of small molecules for castration resistant prostate cancer (CRPC) that bind to the intrinsically disordered N-terminal domain (NTD) of androgen receptor (AR). The work is precedent in the entire field of steroid hormone receptors, with no other small molecule inhibitor reported to bind to the N-terminus of any other steroid hormone receptor.

The successful candidate will join an ongoing collaboration with Dr. Raymond Andersen (drug design and synthesis), Dr. Lin (Chemistry and synthesis of PET imaging agen), and Dr. Strynadka (structural biology) to study the new generation of small molecule inhibitor binding to the N-terminus of steroid hormone receptor, and is expected to conduct laboratory research to design and interpret experiments using proteomic, molecular, biochemical, and genomic tools to thoroughly and robustly quantify changes affecting prostate cancer cell lines/tumor xenografts in response to the new small molecule inhibitor.

The successful scientist will join the laboratory of Dr. Sadar, located in state-of-the-art BC Cancer Research Centre. This is a world-class center for translational cancer research. There are many highly functioning integrated platforms for both basic and translational research such as BC Genome Sciences Centre, the Centre for Translational and Applied Genomics, and the Centre of Excellence for Functional Cancer Imaging, and a superbly equipped proteomics facility. 

Qualifications

The desirable candidate should have experience in molecular biology, mammalian cell culture, and use of genomic tools. Experience with data analysis for large datasets will be beneficial to the candidate.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: PDF_01553_Sadar Lab_2021_12_24 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely on a temporary basis. This restriction would be re-evaluated upon re-contracting.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Genome Sciences Technologist - Library Core

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.:  GST_P00634_HSA 119188_Library Core_2021_12_06

Job Summary

The Genome Sciences Technologist performs various molecular biology techniques and procedures using laboratory robots including biospecimen procurement, sample handling and quality control, diverse library construction and high throughput sequencing methods, in a large scale Genomics production facility. 

Duties

  1. Following controlled laboratory procedures, performs tasks such as biospecimen receipt and quality check, laboratory information management system (LIMS) data entry, RNA and DNA purification, cDNA synthesis, genome and transcriptome next generation library construction and sequencing, Polymerase Chain Reaction (PCR) experiments, and agarose gel electrophoresis.
  2. Works within a regulated quality system including maintaining training records, document control with active corrective and preventative actions (CA/PA).
  3. Data entry using laboratory software and basic reporting of results to supervisors.
  4. Prepares solutions following standard operating procedures.
  5. Maintains general lab and equipment cleanliness.  Recognizes and reports malfunctions in equipment.
  6. Processes patient samples according to established procedures for clinical sequencing diagnostic tests.
  7. Performs other related duties as required.

Qualifications

Education, Training and Experience

  • Graduation from a recognized diploma program in Biotechnology, Microbiology or Biochemistry and two (2) years’ of recent related experience in a research laboratory or an equivalent combination of education, training and experience acceptable to the Genome Sciences Centre Group Leaders and Production Coordinators.

Skills and Abilities

  • Knowledge of molecular biology techniques particularly DNA and RNA preparation and manipulation and a good understanding of genomics technologies.
  • Demonstrated ability to perform detailed procedures reproducibly and accurately.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.
  • Basic knowledge of and ability to operate personal computers.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: GST_P00634_HSA 119188_Library Core_2021_12_06 in the subject line of your email.

This posting will remain online until filled.

Important!

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Genome Sciences Technologist—Library Core

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No. GST_P00634_HSA118077_LibCore_2011_11_15

Job Summary

The Genome Sciences Technologist performs various molecular biology techniques and procedures including library construction which are involved in the operation of a large scale, high throughput DNA mapping and DNA sequencing production facility. 

Duties

  1. Following established laboratory procedures, performs tasks such as colony purification of plasmid/BAC clones, RNA and DNA purification, DNA sequencing, analysis of DNA fingerprints for physical map construction, Polymerase Chain Reaction (PCR) experiments, DNA restriction analysis, agarose gel electrophoresis, southern blot analysis and library construction.
     
  2. Prepares solutions following standard operating procedures.
     
  3. Maintains general lab and equipment cleanliness.  Recognizes and reports malfunctions in equipment.
     
  4. Processes patient samples according to established procedures for clinical sequencing diagnostic tests.
     
  5. Performs other related duties as required.

Qualifications

Education, Training and Experience

Graduation from a recognized diploma program in Biotechnology, Microbiology or Biochemistry and two (2) years’ of recent related experience in a research laboratory or an equivalent combination of education, training and experience acceptable to the Genome Sciences Centre Group Leaders and Production Coordinators.

Skills and Abilities

  • Knowledge of molecular biology techniques particularly DNA and RNA preparation and manipulation.
  • Demonstrated ability to perform detailed procedures reproducibly and accurately.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.
  • Basic knowledge of and ability to operate personal computers.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: GST_P00634_HSA118077_LibCore_2011_11_15 in the subject line of your email.

This posting will remain online until filled.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Process Development Coordinator—CCGI

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Job Reference No: PDC_E00375_CCGI_2021_11_15

Summary

The role of the CCGI at the GSC is to contribute to patient care by developing, validating, and running clinical bioinformatics pipelines and generating clinical patient reports. Reporting to the Group Leader of the Sequencing Team, the Process Development Coordinator will take the lead role in pipeline validation. 

Duties/Accountabilities

  • Oversees the validation and implementation of pipelines into the CCGI team.
  • Takes the lead on validation design, content, and quality assurance documentation.
  • Analyze and assess sequencing data including alignments and variant calling.
  • Perform critical concordance, LoD, sensitivity and specificity analysis and data assessment.

Qualifications

  • Graduation from a recognized Bachelor’s program in an appropriate discipline such as Computer Science, Bioinformatics, Genetics, Molecular Biology or Biochemistry (PhD) preferred);
  • Five (5) years of recent related experience in a research and or clinical laboratory including supervisory experience
     
    OR
     
    An equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Eligibility

  • Experience analyzing and assessing the quality of NGS data, including:
    • short-read alignment and
    • variant-calling (small variants, copy-number variants, fusions),
  • Strong  skills in statistical analysis and data visualization (e.g. with R),
  • Sufficient molecular biology background to take part in designing validations and drawing conclusions from the results,
  • Ability to work independently with minimal oversight,
  • Ability to collaborate with other CCGI members to complete pipeline validations in a timely manner,
  • Strong analytical and written communication skills,
  • High attention to detail, and
  • Experience in experimental design.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: PDC_E00375_CCGI_2021_11_15 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans. As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Project Manager–Personalized OncoGenomics

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RPC_R00022_POG_2021_10_27

Reporting to the Head Project Management or Projects Team Leader and working closely with the Principal Investigators and Project Leaders, the POG Project Manager will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and monitor and facilitate progress against these objectives and milestones. Projects will involve personalized oncogenomics, immunotherapy, collaborative services management, or other cancer genomics research.

Key Responsibilities

  • Actively manage sample acquisition process, ensuring communication amongst the various parties and troubleshooting any deviations
  • Ad hoc sample process development for atypical samples
  • Point person for questions regarding sample acquisition and responsible for leading acquisition team meetings
  • Assist with site administration set up as needed
  • Maintain accurate tracking on sample status, including sample and associated metadata acquisition, processing, stakeholder reporting
  • Coordinate with clinical team for case presentation at tumour board
  • Coordinate and assist the pathology team as needed, including invoice preparation and assistance with sample retrieval
  • Recommend, develop and implement strategies for improving processes
  • Process development as needed, including design, implementation and documentation
  • Assist with clinical data capture
  • Other duties as required

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged.

Qualifications

While equivalencies will be considered, a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus 5 years' recent related experience in project management and/or research development management would be ideal.

Certification as a Project Management professional and experience in academic scientific research or the biotech or software industry will be helpful. Proficiency with MS Word, Excel and Project, excellent organizational, analytical and verbal and written communication skills are essential.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RPC_R00022_POG_2021_10_27 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans. As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Team Leader, Finance

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job reference number: RPM2_R00024_2021_10_18_Finance

Are you proactive, an expert at multi-tasking, and have outstanding attention to details? Do you have experience working with research grant management? Are you interested in contributing to enabling and supporting world-leading cancer research in a dynamic and inclusive team environment? If so, keep on reading as the GSC has an amazing opportunity for a seasoned leader in finance!

The GSC is looking for a new leader for its Finance team.

The GSC has a complex portfolio of projects, funders and partners, with more than 100 accounts and several dozen funders. As Team Leader for Finance, you will lead a team of five finance coordinators in the accounting team for all project accounts for the department, including reconciliation, reporting, accounts payable and receivable, expense authorizations and audit response. You will also be a key member of the Management and Administration Group, working closely with the leaders of project management, people systems, sourcing and procurement and operations. Team leadership includes performance management and ongoing supervision and mentorship of team members, as well as recruitment of new team members as needed. You may also be included in recruitment for other teams, and have opportunities to contribute to and participate in professional development.

Qualifications

Eligibility

  • Communicates with the various departments and levels of management within PHSA, UBC and SFU to ensure we have the most up to date policies and information for the various accounts, cost centres, financial analysis and reports.
  • Monitors expenditures on a regular basis. Reviews all financial information for GSC core operating and grant funds to ensure transactions are eligible and in compliance with funding agencies, BC Cancer, UBC, and SFU etc.
  • Ensures that monthly reconciliation of accounts and records are maintained and summarized for senior management to review.
  • Ensures core and grant-funded budgets remain within allowable spending limits. Manages the follow-up of accounts over budget by initiating remedial action, including withholding allocation to cost centres and communicating potential risks to scientists and senior staff.
  • Provides input into financial policies regarding the appropriate use of funds, approval process, records and reports to ensure the data integrity.
  • Participates in the creation and maintenance of internal controls.
  • Liaises with other groups within the GSC and the Management team to improve processes and procedures.
  • Supervises staff by providing clear responsibilities. Ensures team is provided with excellent training and mentoring opportunities. Monitors workload and ensures work levels meet operational requirements.
  • Provides period and year-end schedule to help coordinate tasks to ensure information is accurate and completed by reporting deadlines. 
  • Works with BC Cancer Research Finance to provide appropriate information required for internal and external audits.

Skills & Abilities

  • Baccalaureate degree from a recognized University in Business Administration and a Professional Accounting designation (CPA), plus 5 to 7 years of recent related experience in grant fund management; or a combination of skills and experience.
  • Experience managing a team of finance professionals.
  • Strong knowledge and working experience with generally accepted accounting principles and finances.
  • Demonstrated analytical and problem solving skills; strong oral and written communication skills.
  • Ability to be flexible to meet and adapt to changes in organizational priorities in a fast paced environment.
  • Excellent Microsoft Office skills, particularly Excel.

Application

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca using Job Reference No: RPM2_R00024_2021_10_18_Finance in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans. As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Postdoctoral Fellow–Bioinformatics

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: PDF_01553_Jones Lab_2021_10_01

The GSC is currently looking for a Post-Doctoral Fellow to work on the Genome Canada funded LSARP, “Canada’s Earth BioGenome project”. 

The successful incumbent will work with the project team to lead the activities on the development, application and validation of novel approaches and workflows in the area of integrated de novo genome assembly over multiple sequencing technologies. They will develop automated bioinformatics workflow as well as assembly submission. They will also work closely together with Earth BioGenome Project (EBP) consortium on the sequencing and assembly standards. The successful incumbent will work with project leaders to ensure all scientific milestones are achieved and contribute to progress reporting as required. There will be expectations to represent the project within the global EBP consortium and the development of outreach materials and website information. Opportunities will exist for further research on the genomic information developed and for scholarly publication.​

Duties

  • Work with multidisciplinary scientists at the GSC and collaborators to analyze whole genome and transcriptome sequence data, and set up collaborative working plans.
  • Develop and maintain bioinformatics pipelines for genome assembly and data analysis.
  • Produce written documentation of algorithms, validations, SOPs, and other processes related to pipeline updates and procedures as required.
  • Present results of bioinformatics software testing internally and externally.
  • Perform literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.
  • Perform other related duties as required.

Eligibility

Skills and Abilities

  • Knowledge of genomics, genome assembly, and genome analysis software.
  • Fluency in one or more programming languages, such as Python, Javascript and SQL.
  • Experience working in a UNIX/Linus environment and writing shell scripts.
  • Previous API development projects using Open API or Rest API is a plus.
  • Excellent communication and organization skills and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
  • Ability for critical thinking and independent learning.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using PDF_01553_Jones Lab_2021_10_01 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Research Associate–Bioinformatics

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values — science, timeliness, respect — to join us on our mission to use genome science for the betterment of health and society.

Job Reference No.; RA_R00006_Jones Lab_2021_09_28

Summary

The GSC is currently looking for a Research Associate to work on the Genome Canada funded LSARP, “Canada’s Earth BioGenome project”. 

The successful incumbent will work with the project team to lead the activities on the development, application and validation of novel approaches and workflows in the area of integrated de novo genome assembly over multiple sequencing technologies. They will develop automated bioinformatics workflow as well as assembly submission. They will also work closely together with Earth BioGenome Project (EBP) consortium on the sequencing and assembly standards. They will work with Project Leaders to ensure all scientific milestones are achieved and contribute to progress reporting as required. There will be expectations to represent the project within the global EBP consortium and the development of outreach materials and website information. Opportunities will exist for further research on the genomic information developed and for scholarly publication.​

Duties

  • Work with multidisciplinary scientists at the GSC and collaborators to analyze whole genome and transcriptome sequence data, and set up collaborative working plans.
  • Develop and maintain bioinformatic pipelines for genome assembly and data analysis.
  • Produces written documentation of algorithms, validations, SOPs, and other processes related to pipeline updates and procedures as required.
  • Presents results of bioinformatics software testing internally and externally.
  • Performs literature searches, testing and validation of new data analysis software related to bioinformatics pipelines.
  • Performs other related duties as required.

Skills and Abilities

  • Expertise in bioinformatics, emphasizing genome sequence analysis and gene annotation.
  • Knowledge and experience using scientific tools, technologies and online resources as pertaining to de novo genome assembly.
  • Fluency in multiple programming languages, including Python, Javascript and SQL.
  • Expertise developing and operating in a UNIX/Linus environment and writing shell scripts.
  • Experience developing custom scripts and pipelines using high performance computing and other available tools. Pipelines may include de novo assembly, annotation, database query, pan-genome construction and visualization tools, RNA-seq, phylogenetic tree reconstruction.
  • Previous API development projects using Open API or Rest API is a plus.
  • Excellent communication and organization skills, and ability to efficiently manage time and workflow, including skillfully prioritizing both long-term projects and day-to-day responsibilities.
  • Ability for critical thinking and independent learning.
  • Experience in a supervisory role is an asset.  

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using RA_R00006_Jones Lab_2021_09_28 in the subject line of your email.

This position will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Process Development Coordinator–Clinical

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values — science, timeliness, respect — to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: PCD_E00375_Clinical_2021_08_11

Reporting to the Bioinformatics Group Leader the Process Development Coordinator (PDC) will support the development, testing and validation of clinical bioinformatics processes at the Genome Sciences Centre (GSC)—a large scale, high throughput biologics facility. The PDC will develop new Clinical procedures and bioinformatic workflows, monitor and review performance within the clinical production process, and where applicable, improve existing analyses.

Scope and complexity

The PDC monitors existing processes and recommends and/or develops new processes in support of the clinical sequencing objectives at the GSC. The PDC designs and performs informatic experiments to validate either existing methods or novel methods providing new functionality. The successful candidate will strive to streamline existing functionality, and maximize output quality and efficiency while balancing costs. Monitoring of results and comparison to outlined standards will be performed.

The PDC collaborates closely with key stakeholders for the clinical process including the clinical director, bioinformatics groups and quality assurance group.

Duties/Accountabilities

Oversees the development and testing of clinical bioinformatics production processes by:

  1. Designing and performing experiments pertaining to the generation of clinically relevant results.  This includes, but is not limited to, the development and testing of new analyses, protocol optimization, Quality Assurance and Quality Control, testing of prototypes and related activities. The PDC continually monitors performance of protocols within the production process and identifies areas for improvement. All activities will yield documented recommendations and implementation plans.
  2. Troubleshooting existing clinical computational processes where necessary. Makes recommendations and adjustments and reports problems.
  3. Training designated members of the clinical bioinformatics group in new or optimized analysis workflows. Writes or revises protocols accordingly.
  4. Performing technical functions related to the Bioinformatics groups of the GSC.
  5. Other related duties as necessary.
     

Qualifications

  • Graduation from a recognized Bachelor’s program in an appropriate discipline such as Computer Science, Bioinformatics, Genetics, Molecular Biology or Biochemistry (PhD) preferred).
  • Five (5) years of recent related experience in a research and or clinical laboratory including supervisory experience

OR

An equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

Skills and knowledge

  • Proven expertise with Python and/or other similar high level languages.
  • Demonstrated ability in R or other similar statistical programming languages and in statistical analysis.
  • Functional knowledge of distributed version control systems, such as Git.
  • Demonstrated experience with next generation/ third generation sequencing technology with an in-depth understanding of standards and guidelines for validating clinical bioinformatics analysis pipelines using these technologies.
  • Excellent verbal and written communication skills.
  • Comfortable working in a Linux environment, including experience with shell scripting and common command-line tools.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.
  • Experience liaising with multiple stakeholders to support consensus goals.
  • Demonstrated ability to efficiently organize work assignments and establish priorities to meet set milestones.
  • Demonstrated ability to write technical documents including validations and procedure manuals
  • Excellent analytical skills
  • Demonstrated ability to accept responsibility and work independently.
  • Experience with bioinformatic workflow managers eg Nextflow would be considered an asset.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using the Job Reference No. PCD_E00375_Clinical_2021_08_11 in the subject line of your email.

This posting will remain online until filled.

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021

We believe that equity, diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Research Project Manager (temporary leave replacement)

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values — science, timeliness, respect — to join us on our mission to use genome science for the betterment of health and society.

Summary

This position is for a temporary 18-month leave replacement.

Job Reference No: RPC-R00022-2021-08-11

Do you have a background in science research — from its processes and practices to proposals & peer-review? Can you develop an award winning grant application, facilitate efficient and productive meetings, gather the right information and engage the right people at the right ti​me? We're looking for a Research Project Manager to help GSC faculty and leaders continue to deliver world-leading genomics, bioinformatics, cancer and precision medicine research.

Reporting to the Head, Project Management or Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and monitor and facilitate progress against these objectives and milestones. Projects will involve personalized oncogenomics, collaborative services management, or other cancer genomics research.

Duties/Accountabilities

  • Establishing budgets for research projects, grants, collaborations and core activities
  • Assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
  • Monitoring budgets and expenditures
  • Establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives, which may include, meeting coordination and follow-up, coordination of case reviews
  • Maintaining accurate information on sample status, including sample and associated metadata acquisition, processing, stakeholder reporting
  • recommending strategies for improving projects management methods and processes
  • Liaising with grant/core funding agencies
  • Interacting directly with research collaborators or clinical study teams as required

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will experience in academic scientific research, clinical trials research, biotech or software industry. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at level Research Project Coordinator, which is equivalent to that described above

Core Skills and Abilities

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Project Manager in the subject line of your email.

This posting will remain online until filled.

Important!

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Research Programmer - Jones Lab

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RP_R00008_Jones Lab_2021_07_30

The GSC is looking for an enthusiastic and self-motivated Research Programmer to work on the next generation of federated genome and health data sharing platform, CanDIG—a Canadian data-sharing platform contributing to the development of an international effort to facilitate information exchange as part of the Global Alliance for Genomics & Health (GA4GH). CanDIG also supports large-scale provincial and national data sharing projects, including BC Cancer’s Personalized OncoGenomics program, the Terry Fox Research Institute's (TFRI) PROFYLE project and the TFRI-led Marathon of Hope Cancer Centres Network—a major federal initiative to accelerate the adoption of precision medicine for cancer in Canada. This role requires a combination of interest in DNA technology and a strong background in software development.

Key Responsibilities

  • Designs, plans and implements computer modeling of research data.
  • Works with other project team members to develop and test code, and implements software.
  • Develops graphical user interfaces.
  • Prepares programming documentation in accordance with prescribed standards.
  • Conducts literature reviews and provides input and recommendations to the Department Head or Principal Investigator regarding new computer applications or statistical techniques.
  • Participates in the lab meetings and presents work for review by others.
  • May provide day to day work direction to others.
  • Provides contributions to the preparation and/or presentation of research papers.

Qualifications

The successful candidate will have an undergraduate degree in computer science, bioinformatics or a related subject.

Abilities

  • 2+ years of experience in Python programming.
  • Previous experience or exposure in the bioinformatics settings.
  • Full stack web development experience with web frameworks such as Flask or Django.
  • Previous experience in designing, implementing and testing REST APIs.
  • General understanding or previous experience in microservice architecture and development.
  • General knowledge in Unix environment, Version Control (Git), and Agile methodologies. 
  • The position requires working with a wide variety of researchers, software developers and clinicians, thus excellent communication skills are essential.

Assets

  • Experience or knowledge in handling genomics data files.
  • Prior experience in developing front-end applications using React.js.
  • Experience building rich queries using GraphQL or other data query language.
  • Experience working with distributed systems.
  • Basic understanding of DNA technology or previous work experience with genetic data is a plus, but not required for the position.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RP_R00008_Jones Lab_2021_07_30 in the subject line of your email.

This posting will remain online until filled.

Important

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Business Analyst and Project Support

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RPC2_R00026_2021_07_06

Reporting to the Manager, QA/QC, the Business Analyst and Project Support (BA) leads the analysis and documentation of business requirements to support projects for designated programs/services. This position works in close collaboration with other stakeholders to develop business systems enhancements, business solutions, or business processes including GSC’s bioinformatics processes. The BA functions as a Subject Matter Expert (SME) to the project team through performing gap analysis of systems and business process mapping including the identification of linkages to other business systems.  

The BA will:

  • Provide key contributions to the development of solutions to ensure that business processes and/or project deliverables are consistent, accurate, and timely.  
  • Participate in and contributes to strategic planning. 
  • Develop project plans for the design, development, and implementation of new business processes, and supports the transition from current systems, practices and processes to an integrated system, common practices, and standardized processes with current or improved functionality.  

Responsibilities

  • Ensures key results are achieved in accordance with the project plan by analyzing current business systems and processes, generating ideas and formulating recommendations/options, and supporting members of the project in prioritizing tasks and reaching decisions that are within project scope and timelines. 
  • Implements or contributes to the implementation of effective processes to assess project risks, identifies risk mitigation strategies and monitors risk throughout the project lifecycle. Supports the Managers/Team Leads by providing regular updates on the progress as well as any areas of risk associated with the completion of the project both within the project scope and the timeline. Provides professional expertise to staff, departments, stakeholders, and guidance regarding standard process for project management.
  • Coordinates and participates in the analysis, acceptance criteria definition, development, testing, training, implementation, and maintenance phases of assigned bioinformatics projects. Carries out post-implementation reviews of systems and makes recommendations for improvements.
  • Utilizes formal data gathering techniques and analysis tools such as flowcharts, diagrams, dashboards, roles and responsibility matrix (RACI), and work effort estimates. Provides details of estimated implementation costs including associated staffing requirements.
  • Reviews, analyzes and defines current/future state processes, determines user and/or department requirements and contributes to the development of specifications and testing for all identified development, system modifications, and installations. Performs impact analyses. 
  • Provides user support, advice and guidance, and orientation in situations that require interpretation and judgement Develops content, as required, for training modules, delivers training, and provides and guidance to system users and department staff. Develops and maintains various business processes, policies and procedures, as well as reference documentation such as user instructions, manuals, and reference materials.  
  • Provides support to colleagues and users during the development, maintenance and operation of various computer systems by performing duties such as troubleshooting system software problems and testing alternative solutions. 
  • Participates in the formal data collection and analysis to help identify system deficiencies and/or operational inefficiencies in order to report and develop new ways of improving business efficiencies including the data analysis related to business case developments, project proposals, and other key strategic and transformative initiatives. 
  • Assembles, creates and maintains information systems technical and operational documentation according to departmental standards.
  • Assists with preparation of Requests for Information/Proposal, development of evaluation processes and tools, and evaluation of vendor responses by serving on working groups, documenting detailed requirements, and coordinating project team and vendor communications.

Education and skills

  • A level of education, training, and experience equivalent to a Bachelor's degree in Health Information Science, Computer Science, or a related discipline, plus five (5) years recent related experience which includes software/system project planning, analysis and implementation.  
  • Demonstrated ability to carry out business process mapping and fit gap analysis.  
  • Excellent interpersonal, oral, and written communication skills with the ability manage multiple interactions with multiple groups while working on multiple issues at the same time.  
  • Superior analytical, problem-solving and system analysis skills.  
  • Proven ability to plan and execute projects with stringent timelines.  
  • Ability to work effectively as part of a team.  
  • Demonstrated ability to provide professional expertise to staff, departments and GSC stakeholders, and guidance regarding standard processes for software/computer system related project management.  
  • Demonstrated ability to provide user support, advice and training, and other user liaison services.
  • Public Service and Health Sector experience and knowledge are an asset.  

How to apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Business Analyst and Project Support in the subject line of your email. 

This posting will remain open until filled.

Important!

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. 

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Research Project Manager

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values — science, timeliness, respect — to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RPC-R00022-2021-05-28

Do you have a background in science research — from its processes and practices to proposals & peer-review? Can you develop an award winning grant application, facilitate efficient and productive meetings, gather the right information and engage the right people at the right ti​me? We're looking for a Research Project Manager to help GSC faculty and leaders continue to deliver world-leading genomics, bioinformatics, cancer and precision medicine research.

Reporting to the Head, Project Management or Projects Team Leader and working closely with the Principal Investigators and Project Leaders, you will play a key role in managing research projects and grants within the context of a research culture with established policies and procedures, vision and values. The major focus of this position is to work with the Principal Investigators and Project leaders to establish the objectives, milestones, and budgets for various research projects and grants, and monitor and facilitate progress against these objectives and milestones. Projects will involve personalized oncogenomics, collaborative services management, or other cancer genomics research.

Duties/Accountabilities

  • Establishing budgets for research projects, grants, collaborations and core activities
  • Assisting with preparing grants, progress reports, statement of work documents, compliance documents, sample status or analysis reports
  • Monitoring budgets and expenditures
  • Establishing, monitoring, and coordinating project progress, milestones, deadlines and objectives, which may include, meeting coordination and follow-up, coordination of case reviews
  • Maintaining accurate information on sample status, including sample and associated metadata acquisition, processing, stakeholder reporting
  • recommending strategies for improving projects management methods and processes
  • Liaising with grant/core funding agencies
  • Interacting directly with research collaborators or clinical study teams as required

Qualifications

While equivalencies will be considered, ideally you bring a degree in Science (preferably Genetics, Biochemistry, Microbiology or Computer Science) plus 5 years' recent related experience in project management and/or research development management.

Certification as a Project Management professional will help you make the short list, as will experience in academic scientific research, clinical trials research, biotech or software industry. Proficiency with MS Word, Excel and Project is essential and you should have excellent organizational, analytical and verbal and written communication skills.

Successful candidate(s) will be offered positions through Provincial Health Services Authority at level Research Project Coordinator, which is equivalent to that described above

Core Skills and Abilities

Excellent written and verbal communication skills and proactive interactions with collaborators are a must to perform successfully in this position. Active participation in laboratory meetings and seminars relevant to the project activities is highly encouraged.

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Project Manager in the subject line of your email.

This posting will remain online until filled.

Important!

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Research Programmer - Data Scientist

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Summary

Job Reference No: RP_R00008_Karssan Lab_ 2021_05_19

Dr. Aly Karsan and the Karsan lab team at Genome Sciences Centre (GSC) are seeking a Research Programmer to join a Marathon of Hope Cancer Centre research project. The team will be working with other research programmers at the Karsan lab for developing data analysis pipelines for various next-generation sequencing (NGS) data such as but not limited to scRNA-Seq, targeted sequencing, ATAC-Seq, and BS-Seq, for the study of cancer evolution. We seek candidates with strong analytical and programming skills to research, develop, and improve our research pipelines.

The role is ideally suited for detail-oriented individuals with a strong interest in data analysis, research, and scientific programming within a high throughput academic setting.  The Karsan lab has a history of strong publications and can offer great experience in research with full access to the GSC’s world-class compute cluster.  Additionally, the Karsan Lab has a diverse computational biology core for knowledge sharing, collaboration, and support. 

Duties/Accountabilities

  • Design and implement bioinformatic data pipelines to meet objectives of the project
  • Work with other project team members to develop and test code, and implement analysis
  • Evaluate and incorporate third-party software into pipelines
  • Produce thorough but concise written documentation of experiments, algorithms, validations, and other procedures as required.

 Qualifications

  • Graduation from a recognized Bachelor of Science Program in Computer Science or relevant program. A Master’s degree in a relevant field would be a strong asset. 
  • Two (2) years of recent related experience or an equivalent combination of education, training, and experience.

Core Skills and Abilities

  • Expertise with scientific programming and able to provide links to code samples via GitHub
  • Familiarity with molecular and cellular biology
  • Excellent verbal and written communication skills
  • Demonstrated ability to interpret results
  • Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
  • Established ability to efficiently organize work assignments and establish priorities
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.

Additional Assets

  • Familiarity in statistical analysis using modern computational tools (experience with any relevant tools will be considered, but R and Python are preferred)
  • Familiarity in next-generation sequencing datasets
  • Understanding of cancer biology
  • Functional knowledge of distributed version control systems, such as SVN or GIT

Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No: RP_R00008_Karssan Lab_ 2021_05_19 in the subject line of your email.

This posting will remain online until filled.

Important!

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

Postdoctoral Fellow, Gastrointestinal Cancers

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position would require working remotely on a temporary basis.


Role Summary

A Post-doctoral position is available immediately for a highly motivated recent PhD or MD/PhD graduate to join a dynamic translational research group, headed by Dr. Isabella Tai, Associate Professor in the Division of Gastroenterology, University of British Columbia and Senior Scientist at Canada's Michael Smith Genome Sciences Centre at BC Cancer.

Current projects in the laboratory revolve around improving our understanding of the mechanisms involved in the development of chemotherapy resistance and metastasis in gastrointestinal cancers (colorectal, gastric, liver and biliary cancers). The goal is to develop either novel therapeutic targets for GI cancer treatment or novel screening tools for diagnosis. We continue to use the latest genomics (including single cell sequencing), proteomics and bioinformatic approaches to identify potential targets or markers for this purpose. Learn more about research projects in the Tai lab here.

Eligibility

Interested individuals with a recent PhD or MD/PhD and strong publication records and excellent academic credentials are encouraged to apply.  Experience in molecular biology, cell biology, tissue culture and animal tumor models, is preferable.  Experience in bioinformatics is an asset.

Duration

Three years (possibility of extension).

To Apply

Please submit a cover letter, curriculum vitae, and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience, long-term career goals and an indication of the desired length of postdoctoral position.

Please email your application to bcgscjobs@bcgsc.ca

Research Programmer

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics, and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.


Job Reference No.: RP_R00008_Karsan Lab_2021_04_19

Role Summary

The Karsan lab team at Canada’s Michael Smith Genome Sciences Centre (GSC) is seeking a research programmer to join a Genome British Columbia software automation project. The team will be working with the Karsan lab, which is responsible for developing high-throughput, clinically accredited pipelines to analyse sequenced data from genomic assays for individualized patient management of cancer. We seek candidates with strong Python software and programming skills to automate and improve existing pipelines and potentially incorporate third-party software into the system.

The role is ideally suited for a creative individual with a strong interest in software development and testing, data analysis, and automation within a high throughput academic setting.

Key responsibilities

  • Design, plan, and implement automated bioinformatics pipelines to meet the objectives of the project
  • Work with other project team members to develop and test code, and implement software
  • Evaluate third-party software and incorporate new systems into legacy systems
  • Produce thorough but concise written documentation of algorithms, validations, SOPs, and other processes and procedures as required

Qualifications

Education, training and experience

  • Graduation from a recognized Bachelor of Science Program in Computer Science. A Master’s degree in a relevant field would be a strong asset. 
  • Two (2) years of recent related experience or an equivalent combination of education, training, and experience acceptable to the project lead.

Core Skills and Abilities 

  • Expertise with Python 3.X and able to provide links to code samples via GitHub or another open repository
  • Comfortable working in a Unix environment, including experience with shell scripting and common command-line tools
  • Familiarity with molecular and cellular biology
  • Excellent verbal and written communication skills.
  • Demonstrated ability to efficiently organize work assignments and establish priorities.
  • Demonstrated interpersonal skills including the ability to work effectively with others in a team environment.

Additional Assets

  • Familiarity in statistical analysis using modern computational tools.  Experience with any relevant tools will be considered, but R and Python are preferred
  • Familiarity with the development, testing, and maintenance of relational databases
  • Familiarity in next-generation sequencing
  • Experience with software testing
  • Experience with Agile software practices
  • Functional knowledge of distributed version control systems, such as SVN or GIT

To Apply

Please submit a detailed cover letter and resume to bcgscjobs@bcgsc.ca, using Job Reference No.: RP_R00008_Karsan Lab_2021_04_19  in the subject line of your email.

This posting will remain online until filled.

Important!

Due to current COVID-19 restrictions, the position would require working remotely within British Columbia on a temporary basis with an ability to come to the normal workplace within reasonable notice. This restriction would be re-evaluated after finalization of reopening plans.

As per the current Public Health Order, full vaccination against COVID-19 is a condition of employment with PHSA as of October 26, 2021.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science.

We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

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