A review of differentiation therapy for myeloid malignancies identifies novel targets for the development of high efficacy drugs with reduced toxicity.
Characterizing transcriptional repressor protein Capicua (CIC) function using a multi-omics approach
Researchers from the lab of Dr. Marco Marra, Director and Distinguished Scientist of the GSC, assess the function of a transcriptional repressor protein using gene knockout.
The GSC’s Dr. Inanç Birol Lab publishes RNA-Scoop, an interactive tool that allows users to visualize differential transcript expression from single-cell transcriptome datasets.
Stopping the cycle: combination therapy reduces growth of androgen-receptor positive breast and prostate cancers
Treating androgen receptor (AR)-positive prostate and breast cancer with two drugs that block AR and cyclin-dependent kinase activity slows proliferation of cancer cells.
Researchers in British Columbia have developed an optimized new protocol for extracting COVID-19 viral nucleic acids for PCR testing using generic reagents, including magnetic beads, on an open-deck liquid handling robot.
Two years ago, no one had ever heard of Bacidia gigatensis. Now, thanks to a team of researchers, science knows a lot about this lichen— including its genomic sequence.
GSC Researchers from the Birol Lab have developed LongStitch, a scalable pipeline for correcting and assembling draft genomes using long reads.
Research on the role Fusobacterium nucleatum plays in cancer shows that the transcriptome and epigenome of different host cell types are affected by the pathogen in different ways.
Using COVID-19 New York patient metatranscriptomics, GSC researchers René Warren and Dr. Inanç Birol, find association between certain HLA alleles and COVID-19 disease severity