We are excited to announce the arrival of the Agilent Femto Pulse System at the GSC! This high-sensitivity automated pulsed-field capillary electrophoresis instrument will be a game changer for nucleic acid quality control - detecting nucleic acids down to 50 fg/µL of DNA or RNA per sample and resolving fragments from 100 base pairs (bp) to over 165 kilobases (kb) in about 1.5 hours.
The Femto Pulse is particularly valuable for supporting our long-read sequencing technologies, such as the Oxford Nanopore PromethION and PacBio Revio. Its ability to accurately size high molecular weight (HMW) DNA ensures optimal sample integrity, critical for generating longer and more accurate reads that are essential for genome assembly, structural variant detection, and complex transcriptomics studies. By integrating the Femto Pulse with our advanced sequencing platforms, we continue to push the boundaries of genomics, supporting groundbreaking discoveries in structural genomics, personalized medicine, and beyond.
We gratefully acknowledge the BC Cancer Foundation and its donors for their generous support in funding the purchase of this essential equipment, which will significantly enhance our research capabilities.