The Terry Fox Research Institute (TFRI) B.C. Node Research Day offers an informative and engaging program of research knowledge translation and exchange. The focus of the 2021 Research Day—which took place in conjunction with the 2021 BC Cancer Summit—was the TFRI Marathon of Hope Cancer Centres Network (MoHCCN) and BC Cancer’s projects and activities in the MoHCCN. Presentations were delivered from each of the seven projects that comprise the launch of MoHCCN at BC Cancer, a presentation from Dr. Jim Woodgett, President of TFRI, and a panel discussion moderated by Stuart McNish, Host of Conversations That Matter. The day was moderated by GSC Director, Dr. Marco Marra, who is the Terry Fox Research Institute, British Columbia Node Leader.
TFRI (B.C. Node) Research Day 2021
Dr. Marco Marra, PhD, FRS(C), FCAHS, OBC, Director, Canada's Michael Smith Genome Sciences Centre (GSC); Distinguished Scientist, BC Cancer Research Institute; Canada Research Chair in Genome Science, Professor, Department of Medical Genetics, Faculty of Medicine, University of British Columbia (UBC); and TFRI, British Columbia Node Leader
Dr. Francois Benard, MD, Senior Executive Director, Research & Distinguished Scientist, BC Cancer Research Institute; BC Leadership Chair in Functional Cancer Imaging, and Professor, Radiology, UBC
Dr. Jim Woodget, PhD, President & Scientific Director, Terry Fox Research Institute; and Senior Scientist, Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital
Dr. Daniel Renouf, MPH, MD, FRCPC, Medical Oncologist, BC Cancer; Assistant Professor of Medicine, UBC; Co-Director of Pancreas Centre BC; and Co-Chair, National Cancer Information Centre, Pancreatic Cancer Disease Group
Dr. Rod Rassekh, MHSc, MD, Investigator, Michael Cuccione Childhood Cancer Research Program, BC Children’s Hospital and Research Institute; and Clinical Assistant Professor, Division of Hematology, Oncology & BMT, Department of Pediatrics, Faculty of Medicine, UBC
Dr. Rebecca Deyel, MHSc, MD, Pediatric Oncologist and Clinician Investigator, BC Children’s Hospital and Research Institute; Co-Lead, Pediatric Precision Oncology Program in B.C.; and Co-Lead, Therapeutics Node, PRecision Oncology For Young peopLE (PROFYLE) program
Dr. Aly Karsan, MD, Distinguished Scientist, GSC, BC Cancer Research Institute; and Professor of Pathology and Laboratory Medicine, UBC
Dr. David Sanford, MD, FRCPC, Clinical Assitant Professor, Vancouver General Hospital (VGH), Leukemia/BMT Program of BC, Division of Hematology, Department of Medicine, UBC
Dr. Janessa Laskin, MD, Medical Oncologist, BC Cancer; Associate Professor, Department of Medicine, UBC; and Clinical Lead of the Personalized OncoGenomics (POG) program
Dr. David Scott, MBChB PhD, Hematologist, Clinician-Scientist, and Clinical Director of the Centre for Lymphoid Cancer, BC Cancer Research Institute
Dr. David Schaffer, MD, FRCPC, Associate Professor, Department of Pathology & Laboratory Medicine, UBC, Head, Department of Pathology and Laboratory Medicine, VGH, and Co-Director of Pancreas Centre BC
Dr. Torsten Nielsen, MD/PhD FRCPC, Clinician-Scientist Pathologist, VGH and BC Cancer; Director, MD/PhD Program, UBC; and former Chair of the CCTG Sarcoma Disease Site Committee
Dr. Martin Hirst, PhD, Distinguished Scientist, Head of Epigenomics, GSC, BC Cancer Research Institute; Professor, Department of Microbiology & Immunology, and Associate Director, Michael Smith Laboratory, UBC
Dr. Stephen Chia, MD, Medical Oncologist, BC Cancer; and Professor & Head, UBC Division of Medical Oncology
Dr. Samuel Aparicio, BM, BCh, PhD, FRCPath, FRSC, Nan & Lorraine Robertson Chair in Breast Cancer Research; Head, Department of Breast Cancer & Molecular Oncology, BC Cancer Research Institute; and Canada Research Chair in Molecular Oncology & Professor in the Department of Pathology & Laboratory Medicine at UBC
Dr. Nadine Caron, MD, MPH, FRCSC, General & Endocrine Surgeon, University Hospital of Northern BC; First Nations Health Authority (FNHA) Chair in Cancer and Wellness, & Professor of Surgery, UBC; Co-Director, UBC Centre for Excellence in Indigenous Health; and Senior Scientist, GSC
00:00:00—Welcome (Dr. Marco Marra)
00:04:20—Introduction to the Marathon of Hope, BC Cancer Consortium (Dr. François Bénard)
00:18:44—Reducing the promise of precision oncology to national practice: The Marathon of Hope Cancer Centres Network supported by the Digital Health Discovery Platform (Dr. Jim Woodget)
01:13:20—BC Cancer Consortium Co-leads (Dr. Renouf)
00:01:15—The Canadian Childhood, Adolescent and young Adult Precision Oncology Initiative (Drs. Rebecca Deyell & Rod Rassekh)
00:29:45—Genomic and epigenomic sequencing to understand resistance and relapse in AML (Drs. David Sanford & Aly Karsan)
00:59:31—Personalized OncoGenomics (POG) program (Dr. Janessa Laskin)
01:29:03—Tumour evolution in aggressive B-cell lymphoma (Dr. David Scott)
00:00:00—The pancreatic cancer precision medicine project (Drs. David Schaeffer & Daniel Renouf)
00:31:48—Sarcomas and epigenetics (Drs. Torsten Neilsen & Martin Hirst)
01:01:50—Nested case control study of shallow whole genome sequencing of cfDNA and WGS/RNASeq of the primary tumour board at the initial presentation of breast cancer (Drs. Samuel Aparicio & Stephen Chia)
01:33:36—Indigenous communities and the Marathon of Hope Cancer Centres Network (Dr. Nadine Caron)
Panelists: Drs. Jim Woodgett, Dan Renouf, Rebecca Deyell, Janessa Laskin, Sam Aparicio, Nadine Caron
Moderator: Stuart McNish