KLEAT is a post-processing tool for cleavage site analysis of transcriptomes. In eukaryotic cells, alternative cleavage of 3’ UTRs can affect transcript stability, transport and translation. For polyadenylated transcripts, cleavage sites can be characterized with short-read sequencing using specialized library construction methods. However, for large-scale cohort studies as well as for clinical sequencing applications, it is desirable to characterize such events using RNA-seq data, as RNA-seq is already widely applied to identify other relevant information on the investigated transcriptomes. CLEAT addresses this need.
Current Release
Released Apr 28, 2015
CLEAT has changed its name to KLEAT. In version 2.0, KLEAT is no longer dependent on the Trans-ABySS analysis framework. Instead, a standalone script is provided to run the assembly and alignments. In addition, the input formats to KLEAT have also been modified to adopt the more standard formats of BAM for alignments and GTF for annotation.
All Releases
| Version | Released | Description | Licenses | Status |
|---|---|---|---|---|
| 2.0 | Apr 28, 2015 | CLEAT has changed its name to KLEAT. In version 2.0, KLEAT is no longer dependent on the Trans-ABySS analysis framework. Instead, a standalone script is provided to run the assembly and alignments. In addition, the input formats to KLEAT have also been modified to adopt the more standard formats of BAM for alignments and GTF for annotation. | BCCA (academic use) | final |
| 1.0 | Mar 28, 2014 | Initial release of CLEAT | BCCA (academic use) | final |