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Acknowledgements

This work was primarily conducted by Malachi Griffith under the supervision of Marco A. Marra. In addition to the authors and funding sources listed below I would like to acknowledge the advice and support of the following people: Joseph Connors, Stephane Flibotte, Steven Jones and Gregg Morin.

Development of ALEXA-seq is ongoing by Malachi Griffith and Obi Griffith under the supervision of Elaine Mardis and Joe Gray respectively.


Citations:

Malachi Griffith and Marco A. Marra.
Alternative expression analysis: experimental and bioinformatic approaches for the analysis of transcript diversity. 2007. Chapter 12. Genes Genomes and Genomics, Volume 2. p201-242. Regency Publications.
Download: PDF


Malachi Griffith, Michelle J. Tang, Obi L. Griffith, Ryan D. Morin, Susanna Y. Chan, Jennifer K. Asano, Thomas Zeng, Stephane Flibotte, Adrian Ally, Agnes Baross, Martin Hirst, Steven J.M. Jones, Gregg B. Morin, Isabella T. Tai and Marco A. Marra.
ALEXA - A microarray design platform for alternative expression analysis. Nature Methods. Feb 2008. 5(2):118.
Download: Pubmed | Full text | PDF | Supplementary Information


Malachi Griffith, Griffith OL, Mwenifumbo J, Morin RD, Goya R, Tang MJ, Hou YC, Pugh TJ, Robertson G, Chittaranjan S, Ally A, Asano JK, Chan SY, Li I, McDonald H, Teague K, Zhao Y, Zeng T, Delaney AD, Hirst M, Morin GB, Jones SJM, Tai IT, Marco A. Marra. Alternative expression analysis by RNA sequencing. Nature Methods. 2010 Oct;7(10):843-847.
Download: Pubmed | Full text | PDF | Supplementary Information | GEO (GSE23776) | News and Views | Press Release


Malachi Griffith, Jessica E. Paul, Trevor J. Pugh, Michelle J. Tang, Ying-Chen Claire Hou, Ryan D. Morin, Jennifer K. Asano, Adrian Ally, Lisa Miao, Pierre Cheung, Alison Lee, Susanna Y. Chan, Greg Taylor, Tesa Severson, Grace S.W. Cheng, Karen Novik, Richard Moore, Sharlene Gill, David Owen, Carl J. Brown, Gregg B. Morin, Isabella T. Tai1 and Marco A. Marra.
Novel mRNA isoforms and mutations of uridine monophosphate synthetase are associated with fluorouracil resistance in colorectal cancer. (Characterization of a single candidate gene in cell lines and a clinical cohort)
Download: In preparation | Data Files


Funding

We are grateful for funding provided by the following organizations: the University of British Columbia, Faculty of Graduate Studies and Faculty of Medicine, Michael Smith Foundation for Health Research, Natural Sciences and Engineering Research Council, Genome British Columbia, Terry Fox Foundation, National Cancer Institute of Canada and BC Cancer Foundation.


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Button link to main ALEXA home page Button link to ALEXA-Arrays home page Button link to ALEXA-Seq home page Button link to acknowledgements of funding and other support for Malachi Griffith and Marco Marra Button link to contact information for Malachi Griffith and Marco Marra