Order	SeqName	SeqType	IsAE	NBL01_MYCN	NBL05_MYCN	NBL09_MYCN	NBL10_MYCN	NBL02	NBL03	NBL04	NBL06	NBL07	NBL08	NBL11_Rel2	NBL11_Rem1	NBL11_Rel1	NBL12_Rel_Left	NBL12_Rel_Right	NBL13_Rel_Left	NBL13_Rel_Right	NBL14_MYCN_Met	NBL14_MYCN_Pri	NBL15_MYCN_Rel1	SKP01	SKP02	SKP03
1	PHKB	Gene	0	116.28	144.69	101.72	68.26	136.32	89.43	97.85	83.21	115.60	134.35	147.95	167.76	202.92	169.49	149.78	104.44	147.16	158.15	66.25	137.82	64.23	55.52	40.09
2	455779	Transcript	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
3	299167	Transcript	0	117.65	132.94	125.96	85.04	120.46	71.95	78.57	82.76	111.25	190.75	165.09	91.68	168.50	207.49	158.72	116.12	154.28	366.66	79.25	146.18	114.04	88.79	41.32
4	323584	Transcript	0	0.00	0.00	0.00	1.70	0.00	0.00	6.23	1.81	6.11	1.32	0.00	0.00	6.33	0.00	0.00	0.00	0.00	0.00	0.00	0.00	11.92	0.00	0.00
5	427582	Transcript	0	31.36	13.42	10.95	18.83	31.31	23.32	18.20	11.06	18.20	9.12	11.86	14.50	20.09	25.85	15.04	9.36	24.70	14.35	8.55	16.21	5.66	6.29	10.47
6	ER1a	ExonRegion	0	1.17	2.59	0.00	0.00	1.85	4.36	1.28	0.66	1.70	2.89	3.33	0.00	0.00	4.93	3.60	1.33	1.48	0.25	1.76	8.22	1.22	0.00	1.92
7	ER1b	ExonRegion	1	35.64	30.05	9.01	6.04	42.22	62.18	62.91	12.27	25.33	35.91	103.46	8.97	6.49	80.65	52.37	85.35	144.51	134.83	35.97	74.15	77.69	33.27	49.45
8	E1a_E2a	KnownJunction	0	0.00	3.29	2.54	0.00	0.00	14.20	12.72	2.55	4.98	8.84	5.37	0.00	0.00	0.00	0.00	0.00	0.00	14.01	0.00	6.39	2.72	0.00	0.00
9	E1a_E3a	KnownJunction	0	0.00	0.00	0.00	1.70	0.00	0.00	6.23	1.81	6.11	1.32	0.00	0.00	6.33	0.00	0.00	0.00	0.00	0.00	0.00	0.00	11.92	0.00	0.00
10	I1	Intron	0	10.42	7.45	10.57	12.92	12.71	13.66	23.46	10.39	21.82	13.11	6.65	30.88	43.38	14.70	13.26	15.81	21.32	17.65	8.28	29.43	4.64	7.68	8.79
11	I1_SR1	SilentIntronRegion	0	1.91	3.37	4.03	4.67	4.09	6.52	4.31	2.99	9.18	6.48	4.09	0.70	3.55	8.46	11.85	14.31	16.09	33.42	3.50	18.71	6.39	2.76	6.43
12	I1_SR2	SilentIntronRegion	0	7.52	8.61	13.56	12.03	12.69	13.99	20.93	8.50	22.43	13.74	9.66	14.28	30.59	22.66	20.30	20.74	29.46	30.92	8.83	30.02	8.87	3.97	10.21
13	I1_AR2	ActiveIntronRegion	1	13.73	7.82	10.62	15.56	14.63	15.19	29.38	13.22	24.84	14.57	5.69	47.45	60.10	11.84	10.09	13.94	18.37	7.62	9.11	32.27	2.06	11.02	8.75
14	E2_Aa	NovelBoundary	0	18.00	6.45	18.10	14.32	32.26	34.24	60.46	14.50	40.54	8.22	7.16	46.67	83.11	12.60	8.90	28.11	44.04	23.88	31.53	59.32	5.75	2.69	4.35
15	ER2a	ExonRegion	1	11.17	25.78	16.44	18.80	19.14	25.30	32.51	21.57	38.58	54.71	83.60	71.01	77.18	47.43	21.66	19.03	129.68	77.46	30.18	86.63	45.18	18.47	19.35
16	E2a_E3a	KnownJunction	1	16.23	24.60	26.99	31.86	39.56	41.34	62.67	44.65	62.96	98.18	231.48	119.29	103.73	145.15	54.52	88.87	309.40	185.96	72.10	179.42	97.98	31.11	42.00
17	ER3a	ExonRegion	0	24.22	28.97	25.26	23.84	75.57	43.83	69.82	43.75	75.66	97.46	175.96	135.08	151.80	197.94	100.38	147.75	198.71	262.91	70.33	181.70	83.59	51.83	60.72
18	E3a_E4a	KnownJunction	0	29.12	34.47	31.58	21.14	62.05	30.15	66.77	35.00	93.66	103.79	154.88	146.00	131.48	135.56	65.64	85.36	181.21	263.23	63.81	136.02	81.73	46.60	48.06
19	ER4a	ExonRegion	0	18.45	56.44	21.30	25.31	41.33	46.87	73.99	47.12	82.73	106.85	129.71	108.58	129.60	185.68	88.87	126.39	158.09	199.77	54.49	158.98	89.37	46.30	34.46
20	E4a_E5a	KnownJunction	0	24.23	87.48	11.38	27.20	28.95	56.10	60.68	59.56	68.29	104.41	147.51	123.94	152.59	176.29	103.71	62.72	184.20	158.14	26.92	173.09	91.06	42.80	38.93
21	ER5a	ExonRegion	0	48.68	62.19	27.42	24.37	71.68	77.29	69.14	46.98	83.62	107.95	181.91	100.49	126.21	207.51	118.23	122.93	210.86	252.03	56.83	189.87	111.22	59.90	39.88
22	E5a_E6a	KnownJunction	0	130.54	91.10	54.29	36.59	182.77	161.84	131.03	57.34	104.66	132.43	263.44	132.04	277.90	320.86	228.69	219.60	250.21	380.75	127.91	251.77	138.63	95.83	57.71
23	ER6a	ExonRegion	0	58.40	73.11	32.03	31.70	74.40	83.03	104.84	54.03	89.00	128.76	212.71	138.78	184.04	224.90	96.63	122.02	228.62	226.52	64.83	209.81	93.64	57.18	42.74
24	E6a_E7a	KnownJunction	1	65.49	82.81	23.48	25.74	72.07	102.21	137.13	58.98	96.30	142.61	226.16	118.24	248.52	246.28	98.65	84.51	201.87	154.95	50.54	198.08	72.09	60.13	46.44
25	ER7a	ExonRegion	0	42.57	93.80	35.70	47.01	98.87	82.50	102.24	64.72	109.79	155.95	227.41	203.48	251.24	228.52	110.39	112.54	202.78	203.57	72.59	233.44	54.00	52.22	50.10
26	E7a_E8a	KnownJunction	0	44.90	96.10	52.48	58.27	92.28	67.35	110.63	68.72	106.34	154.91	222.53	254.03	261.83	189.83	102.48	119.63	172.04	187.83	75.77	226.97	73.39	45.80	48.14
27	ER8a	ExonRegion	0	41.75	91.27	41.72	43.14	86.78	92.13	111.42	80.12	112.19	145.34	235.21	219.98	247.48	234.24	108.07	147.99	208.84	223.93	67.72	178.63	86.69	56.34	52.45
28	E8a_E9a	KnownJunction	1	34.38	125.18	52.01	49.28	93.55	91.20	87.88	71.10	103.59	143.58	163.52	220.87	252.91	234.92	78.37	168.59	231.60	295.48	126.31	183.51	131.71	78.13	58.22
29	ER9a	ExonRegion	1	53.81	106.13	59.26	44.63	91.98	92.06	90.32	64.17	99.72	129.99	224.76	272.28	223.80	292.93	86.86	143.08	274.13	268.70	94.52	189.56	121.14	50.36	72.91
30	E9a_E10a	KnownJunction	1	57.12	125.64	53.49	32.20	70.71	89.04	107.36	64.69	114.23	128.70	223.32	268.74	136.35	313.15	45.99	94.42	243.10	220.78	58.83	176.09	120.53	39.92	56.34
31	ER10a	ExonRegion	1	55.14	156.37	56.88	34.84	72.05	73.54	75.02	59.70	120.46	123.70	229.17	208.08	220.87	279.40	106.29	152.10	248.98	237.07	59.79	168.02	123.38	61.33	46.53
32	E10a_E11a	KnownJunction	0	83.64	272.12	84.53	37.16	116.38	48.78	97.03	72.41	117.33	127.38	192.10	178.11	255.83	307.44	143.27	227.38	279.10	288.18	115.11	183.95	84.70	116.47	66.24
33	ER11a	ExonRegion	0	68.97	186.71	81.13	49.26	145.27	99.73	123.13	73.17	128.23	154.55	196.09	334.92	389.53	243.89	105.37	114.85	193.95	176.33	69.98	209.17	62.26	80.59	43.63
34	E11a_E12a	KnownJunction	0	72.61	167.27	90.77	68.09	193.80	93.13	129.18	104.33	153.12	190.85	221.64	459.15	408.58	218.79	133.38	102.79	170.45	98.62	61.93	273.57	29.16	70.23	32.27
35	ER12a	ExonRegion	1	64.44	211.25	102.00	78.25	150.90	89.19	142.12	96.94	164.21	203.02	226.45	505.88	409.33	190.86	106.95	81.73	179.10	107.62	43.44	218.56	32.07	90.35	21.37
36	E12a_E13a	KnownJunction	1	92.61	356.78	109.93	102.58	161.55	76.77	167.02	91.43	173.61	201.55	186.99	537.48	303.06	252.87	136.35	103.14	198.88	90.95	38.21	232.08	45.59	127.06	38.67
37	ER13a	ExonRegion	1	63.12	235.11	73.46	64.47	126.10	104.74	107.58	95.18	139.17	189.97	205.66	425.90	442.25	162.06	119.58	131.38	198.90	144.50	80.41	222.99	49.92	96.88	49.81
38	E13a_E14a	KnownJunction	1	108.61	231.93	86.57	56.44	143.55	115.16	143.35	98.33	134.72	226.10	170.73	367.32	508.25	156.45	130.91	142.01	206.17	164.32	109.84	218.85	56.90	97.42	60.52
39	ER14a	ExonRegion	0	58.05	185.41	81.37	55.54	136.75	89.31	129.03	91.35	137.88	189.86	226.61	376.36	295.88	237.21	108.79	135.73	250.68	131.99	82.52	201.89	83.69	79.06	46.45
40	E14a_E15a	KnownJunction	0	55.86	148.53	101.36	63.06	113.41	99.43	130.94	99.19	142.74	193.70	225.69	255.98	280.66	268.94	132.27	142.78	223.75	220.61	96.85	151.42	96.50	72.13	51.22
41	ER15a	ExonRegion	1	75.50	148.15	78.62	43.41	149.48	104.02	106.10	84.51	135.81	156.22	278.24	297.27	335.51	287.30	107.90	146.57	259.55	279.48	93.41	188.42	132.94	74.06	65.38
42	E15a_E16a	KnownJunction	0	38.67	166.48	71.64	41.32	113.41	106.81	91.73	76.56	114.87	122.95	192.52	305.20	286.51	270.29	124.11	120.22	189.71	309.78	68.05	157.17	136.59	87.99	65.47
43	ER16a	ExonRegion	0	56.35	156.00	71.14	46.09	135.94	111.14	86.93	78.34	140.96	148.65	237.50	269.12	261.05	268.27	137.55	167.87	205.66	310.69	91.58	180.17	120.30	72.66	62.88
44	E16a_E17a	KnownJunction	0	99.80	174.38	79.71	53.14	206.54	137.42	103.91	85.52	155.00	180.38	269.96	256.88	242.68	280.71	157.49	222.59	191.30	267.25	134.40	176.41	109.16	68.89	65.05
45	ER17a	ExonRegion	1	71.22	213.66	73.50	44.58	188.84	116.29	140.21	88.54	153.78	167.42	264.93	236.88	219.48	295.75	112.01	180.35	254.52	296.90	79.36	187.37	148.63	74.61	56.55
46	E17a_E18a	KnownJunction	0	79.64	265.81	79.92	49.08	139.05	107.95	178.68	75.12	155.87	167.08	215.84	293.20	234.72	233.92	156.38	145.09	243.48	289.01	64.57	193.80	86.36	90.87	58.82
47	ER18a	ExonRegion	0	85.06	203.07	78.92	60.15	143.12	103.48	120.94	88.30	151.40	179.95	221.66	300.69	302.12	263.18	142.99	139.12	237.63	298.96	89.76	174.32	147.88	69.72	46.99
48	E18a_E19a	KnownJunction	0	72.24	219.70	102.39	72.55	172.58	134.87	155.54	92.50	177.72	215.65	247.54	288.39	234.56	245.75	119.91	142.87	301.07	338.80	145.42	172.13	157.41	86.16	46.18
49	ER19a	ExonRegion	0	102.34	258.88	78.98	73.43	190.67	119.72	157.55	92.89	150.97	190.16	270.48	276.84	264.47	239.98	107.37	169.30	266.18	228.61	99.99	182.98	88.00	85.70	71.49
50	E19a_E20a	KnownJunction	0	186.63	426.17	71.94	72.02	287.35	145.37	268.77	103.01	132.72	186.91	276.86	314.05	304.36	213.43	108.04	161.75	168.86	178.21	109.65	202.49	93.65	74.22	68.29
51	ER20a	ExonRegion	0	121.92	348.18	88.67	87.24	163.06	103.11	192.93	111.08	151.53	185.47	233.37	300.30	344.01	237.79	145.24	137.00	238.86	200.18	104.73	199.28	61.65	78.92	57.39
52	E20a_E21a	KnownJunction	0	150.25	345.33	96.83	93.33	190.32	124.02	206.33	112.63	176.76	184.08	218.63	321.40	312.64	192.42	174.18	128.43	234.22	193.30	126.78	186.38	64.06	84.75	71.88
53	ER21a	ExonRegion	0	133.85	271.23	86.33	97.00	182.24	103.44	151.88	100.54	163.51	183.11	224.70	333.61	402.47	242.99	159.79	194.43	248.37	211.94	130.25	182.81	58.89	88.38	87.91
54	E21a_E22a	KnownJunction	0	176.77	243.44	122.59	129.72	160.36	157.98	154.04	126.47	189.47	226.77	214.16	377.37	468.64	324.92	277.03	277.62	237.03	320.93	244.34	250.87	57.82	138.69	112.59
55	ER22a	ExonRegion	0	124.02	225.43	143.29	104.24	165.46	104.85	121.25	124.62	208.52	219.78	260.04	322.06	426.57	299.49	205.90	200.52	248.79	308.16	137.43	245.57	95.11	118.56	89.05
56	E22a_E23a	KnownJunction	0	143.66	350.40	154.84	85.34	205.35	104.88	168.83	116.77	204.22	214.79	315.03	352.31	670.25	227.97	258.24	162.44	243.57	264.76	111.06	210.48	134.24	103.61	44.30
57	ER23a	ExonRegion	0	123.64	285.69	125.21	86.72	207.49	117.57	185.44	122.21	185.71	209.63	245.69	284.36	440.66	298.32	216.97	236.91	248.40	403.74	142.76	207.14	121.87	103.86	81.65
58	E23a_E24a	KnownJunction	0	142.32	205.56	125.45	103.55	210.10	112.89	150.73	127.29	165.19	207.67	269.12	270.69	347.06	284.72	171.33	182.69	190.28	445.21	137.23	187.09	139.18	98.59	83.40
59	ER24a	ExonRegion	0	93.98	187.16	97.37	74.79	188.80	110.52	119.80	116.71	151.09	189.38	243.36	201.43	346.83	256.43	212.11	148.14	229.33	343.75	120.89	201.53	126.66	74.65	60.45
60	E24a_E25a	KnownJunction	0	92.83	170.30	89.44	58.30	175.21	115.73	95.97	97.06	135.53	147.15	152.09	155.00	392.67	321.33	218.68	153.38	141.19	223.72	105.60	220.39	95.88	60.19	54.03
61	E25_Aa	NovelBoundary	1	3.70	17.04	0.00	3.26	12.31	5.45	3.89	6.04	4.17	5.53	4.47	31.36	107.79	2.47	8.90	7.95	13.46	7.42	0.00	0.00	0.00	11.82	0.00
62	ER25a	ExonRegion	0	83.42	114.79	103.29	72.21	127.51	89.51	64.65	80.46	115.63	154.12	180.06	171.76	303.72	249.58	186.68	156.09	156.56	270.54	101.60	168.78	92.75	82.91	50.23
63	E25_Da	NovelBoundary	0	16.08	13.88	6.48	12.99	15.45	12.95	52.47	16.55	46.61	27.69	36.06	37.81	104.05	33.49	4.45	45.12	48.15	23.13	21.55	10.99	10.38	27.56	8.11
64	E25a_E26a	KnownJunction	0	0.00	0.00	1.74	8.72	0.00	0.00	0.00	0.00	1.56	2.58	0.00	0.00	0.00	0.00	4.45	0.00	0.00	0.00	3.67	3.26	0.00	0.00	0.00
65	E25a_E27b	KnownJunction	0	117.65	132.94	125.96	85.04	120.46	71.95	78.57	82.76	111.25	190.75	165.09	91.68	168.50	207.49	158.72	116.12	154.28	366.66	79.25	146.18	114.04	88.79	41.32
66	E25a_E28a	NovelJunction	0	3.78	0.00	1.18	2.06	0.00	5.68	10.64	0.00	3.33	1.53	7.00	0.00	0.00	2.12	18.54	8.29	0.00	1.70	0.00	2.88	2.84	2.82	0.00
67	I25	Intron	0	10.73	14.66	4.36	20.29	23.28	19.23	20.40	12.29	31.75	18.26	14.32	38.97	57.27	22.19	9.50	19.21	20.84	9.46	5.07	19.57	3.07	12.22	5.98
68	I25_AR1	ActiveIntronRegion	0	10.30	16.50	4.71	17.82	21.49	16.87	20.52	11.34	30.48	16.94	15.76	35.36	57.49	23.47	9.46	19.47	21.61	9.37	6.10	18.58	3.53	13.71	6.93
69	I25_SR1	SilentIntronRegion	1	10.90	11.71	3.68	31.40	33.48	29.42	19.42	18.14	41.74	21.27	10.08	61.96	67.89	20.97	5.73	14.28	18.20	10.21	1.03	25.69	1.53	8.37	2.96
70	I25_AR2	ActiveIntronRegion	0	14.19	4.82	2.70	22.40	21.32	21.93	21.52	10.55	26.06	24.49	9.89	30.86	38.87	14.22	16.36	25.71	19.35	9.16	3.46	17.72	1.95	6.74	3.41
71	E26_Aa	NovelBoundary	0	10.82	31.51	1.30	16.41	15.70	20.61	32.59	23.37	30.12	29.44	19.43	37.66	55.84	43.09	4.45	43.83	20.38	8.21	4.33	40.65	6.18	2.57	3.33
72	ER26a	ExonRegion	1	13.82	10.84	1.00	8.97	27.17	12.33	15.38	4.62	15.66	10.17	8.60	26.74	49.89	23.31	9.50	9.05	19.04	5.62	0.60	13.02	2.76	5.08	1.94
73	E26_Da	NovelBoundary	0	74.24	29.86	4.49	12.02	35.31	42.36	24.82	7.02	30.47	29.76	27.22	23.41	86.52	29.67	32.14	34.95	9.07	7.67	3.76	24.29	5.75	13.66	3.76
74	E26a_E28a	KnownJunction	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
75	I26	Intron	0	22.79	17.64	5.42	18.33	28.98	29.69	21.04	17.70	33.11	20.30	13.50	30.70	50.57	19.17	10.81	17.47	15.76	8.68	7.97	17.22	4.62	13.95	7.52
76	I26_AR1	ActiveIntronRegion	0	22.85	17.68	5.43	18.37	29.04	29.76	21.09	17.74	33.18	20.35	13.53	30.77	50.69	19.22	10.83	17.51	15.79	8.70	7.99	17.25	4.63	13.98	7.54
77	E27_Aa	NovelBoundary	0	42.82	32.95	10.94	34.73	16.21	26.52	20.01	34.87	27.43	28.61	12.11	12.60	13.47	24.37	23.86	38.88	21.32	16.29	8.47	40.14	9.88	10.72	4.18
78	ER27a	ExonRegion	0	31.36	13.42	10.95	18.83	31.31	23.32	18.20	11.06	18.20	9.12	11.86	14.50	20.09	25.85	15.04	9.36	24.70	14.35	8.55	16.21	5.66	6.29	10.47
79	E27_Ab	KnownBoundary	0	35.19	16.58	24.48	43.15	43.21	40.20	22.30	27.72	41.38	18.86	4.90	17.11	20.94	55.86	19.90	7.60	35.06	20.06	18.35	37.33	8.59	13.35	23.47
80	ER27b	ExonRegion	0	185.57	188.04	120.45	89.78	190.33	146.17	111.87	107.64	145.63	200.73	235.77	161.73	304.02	252.15	232.23	173.34	218.74	302.70	110.50	207.23	117.43	77.00	60.46
81	E27a_E28a	KnownJunction	0	215.96	164.58	87.70	80.08	189.22	140.83	130.28	96.98	127.34	200.50	234.06	198.96	220.60	222.62	189.26	135.09	191.68	206.23	69.55	209.71	86.92	76.11	48.74
82	ER28a	ExonRegion	0	183.40	175.11	159.22	111.65	210.96	127.13	131.42	124.67	183.72	205.56	229.29	192.67	261.42	285.67	271.19	167.17	216.54	259.11	116.96	207.89	116.26	89.54	65.05
83	E28a_E29a	KnownJunction	0	258.49	188.72	242.81	141.01	224.28	117.26	138.45	145.28	161.60	205.44	214.79	201.82	257.13	244.16	339.08	215.33	232.16	372.67	132.62	255.54	136.90	102.50	85.45
84	ER29a	ExonRegion	0	195.06	174.29	208.81	105.98	211.11	155.79	124.94	136.23	205.93	212.71	254.41	206.66	233.84	284.41	324.38	178.75	219.69	360.31	113.56	227.88	151.01	84.11	78.46
85	E29a_E30a	KnownJunction	0	271.83	232.20	226.84	122.56	386.16	252.58	190.03	163.60	193.92	225.64	263.65	224.32	231.15	382.54	410.41	186.70	274.61	349.95	129.04	275.42	140.54	99.57	66.58
86	ER30a	ExonRegion	0	217.09	168.02	234.88	120.83	233.57	146.93	155.33	147.38	193.30	245.46	210.64	197.29	247.74	304.65	356.88	195.29	247.77	293.95	121.36	212.01	122.68	79.17	72.15
87	E30a_E31a	KnownJunction	0	230.63	214.76	184.35	107.21	241.60	171.27	132.31	148.28	197.22	244.79	181.57	112.54	233.75	328.86	294.09	155.77	263.02	149.32	68.05	190.09	108.54	62.52	42.00
88	ER31a	ExonRegion	0	266.23	215.18	224.91	113.62	248.75	181.44	142.82	144.31	198.76	223.24	220.35	149.45	233.46	262.34	297.73	149.93	221.83	182.09	91.20	191.04	89.50	78.15	51.88
89	E31a_E32a	KnownJunction	0	406.29	344.87	277.19	174.34	426.83	261.55	249.92	223.03	249.25	334.49	230.58	167.15	237.16	255.34	370.11	234.13	271.90	289.55	210.08	241.80	87.23	116.65	109.09
90	ER32a	ExonRegion	0	370.98	255.03	216.45	138.72	335.97	210.61	199.59	170.70	197.57	235.64	218.25	167.90	390.37	268.86	327.22	164.46	203.37	197.96	112.30	195.46	72.30	72.58	50.26
91	E32a_E33a	KnownJunction	1	529.65	295.87	250.43	156.62	279.20	176.09	167.55	213.22	252.34	256.91	217.48	173.01	435.52	281.42	568.52	198.92	238.71	200.84	146.73	248.32	101.13	91.18	69.83
92	ER33a	ExonRegion	0	134.79	123.21	115.12	74.12	123.77	71.24	72.62	76.76	89.60	95.95	63.92	94.79	116.33	79.05	138.77	49.54	56.75	56.45	38.15	72.58	22.74	35.09	20.12