The archive 'overlap_analysis_results_gene_details.zip' contains 14 files. These files represent the detailed overlap analysis results for all genes for each comparison group (e.g. cancer vs non-cancer) The files have been sorted on Entrez_id. Note about file names: Each file is named in the format: conditionSet1_vs_conditionSet2 For example, one file might summarize all genes from the cancer versus non-cancer analysis. In this case, all genes that were identified in one or more comparisons that compared cancer samples (FTC, PTC, etc) to non-cancer (FA, Norm, etc) samples would be included. Detailed information from the original publication, mappings, and additional analysis are provided for each gene. The column headings are defined as follows: Study: Study number Comparison: Comparison number Entry: Unique entry number Entrez_id: NCBI Entrez Gene identifier (e.g. 29) Entrez_name: NCBI Entrez Gene name (e.g. ABR) Entrez_description: NCBI Entrez Gene description Map_method: Method of mapping to Entrez Gene (e.g. affy_probe_2_Entrez) n_studies: Total number of studies identifying gene X in the comparison group n_comparisons: Total number of comparisons identifying gene X in the comparison group n_total_samples: Total reported samples net_fold_change: Net Fold change (Simple sum of positive and/or negative fold-changes) net_direction: Net Direction(up, down or even. e.g. If one study reported gene X as up- and two studies reported it as down-regulated, then net_direction='down') net_direction_score: Net Direction Score (e.g. For the case above, net_direction_score=1-2=-1) n_disagreements: Number of disagreements from dominant fold-change direction (e.g. For the case above, n_disagreements=1) up_down: Number of fold-changes reported as up- vs. down-regulated (e.g. For the case above, up_down='1/2') avg_fold_change: Sum of reported fold-changes for gene X over the number of comparisons actually reporting a fold-change n_comparisons_FC: Number of comparisons actually reporting a fold-change for gene X n_total_samples_FC: Number of total samples for comparisons actually reporting a fold-change for gene X max_fold_change: Maximum fold change observed for gene X min_fold_change: Minimum fold change observed for gene X Probe_Tag_Acc: Probe, Tag or Accession identifier used for mapping to Entrez Gene ID. Probe: Probe identifier for gene X (for Affymetrix datasets) Tag: tag sequence (for SAGE datasets) Accession: Acccession identifier (for cDNA arrays) Description: Description provided by original publication or supplementary materials (replaced by Entrez_description after mapping) Gene: Gene Symbol/Name provided by original publication or supplementary materials (replaced by Entrez_name after mapping) Fold_change: Fold-change provided by original publication or supplementary materials Std_Fold_Change: Standardized fold change (e.g. fold change of 0.5 was converted to -2) up_down_cond1_vs_cond2: Direction of fold-change provided by original publication or supplementary materials (for condition 1 vs. condition 2) RT-PCR: yes/no value indicating whether gene was validated by RT-PCR. Not comprehensively reviewed for all genes or studies. Western: yes/no value indicating whether gene was validated by Western Blot. Not comprehensively reviewed for all genes or studies. IHC: yes/no value indicating whether gene was validated by Immunohistochemistry. Not comprehensively reviewed for all genes or studies. Class_predictor: yes/no value indicating whether gene was useful in a class prediction model. Signif: yes/no value indicating whether a gene was reported as statistically significant - Generally this was implied. Pvalue_listed: Actual p-value provided for gene in original publication or supplementary materials. Cond1: Condition 1 in comparison (e.g. FTC. Note: fold change direction requires careful of definition of what is being compared to what) Cond2: Condition 2 in comparison (e.g. FA. Note: see Cond1 note) n_cond1: Number of samples for condition 1 in comparison. n_cond2: Number of samples for condition 2 in comparison. Source: Source of data (publication, supplementary materials, etc) Comment: Any specific comments. PMID: Pubmed identifier for source publication.