/* Last changed Time-stamp: <2008-06-27 17:21:42 ivo> */ /** *** \file fold_vars.c *** global variables to change behaviour of folding routines
*** Also there are some functions that make the live easier when *** using functions of the Vienna RNA package **/ #include #include #include "fold_vars.h" int circ = 0; int noGU = 0; /* GU not allowed at all */ int no_closingGU = 0; /* GU allowed only inside stacks */ int tetra_loop = 1; /* Fold with specially stable 4-loops */ int energy_set = 0; /* 0 = BP; 1=any with GC; 2=any with AU parameters */ int dangles = 2; /* use dangling end energies */ char *nonstandards = (char *)0; /* contains allowed non standard bases */ double temperature = 37.0; int james_rule = 1; /* interior loops of size 2 get energy 0.8Kcal and no mismatches (no longer used) */ int oldAliEn = 0; /* use old alifold-energies (without removing gaps) */ int ribo = 0; /* use ribosum instead of classic covariance term */ char *RibosumFile = NULL; /* TODO: compile ribosums into program Warning: this variable will vanish */ int csv = 0; /*generate comma seperated output*/ bondT *base_pair; FLT_OR_DBL *pr; /* base pairing prob. matrix */ int *iindx; /* pr[i,j] -> pr[iindx[i]-j] */ double pf_scale=- 1; /* scaling factor to avoid floating point overflows */ int fold_constrained = 0; /* fold with constraints */ int do_backtrack=1; /* calculate pair prob matrix in part_func() */ int noLonelyPairs = 0; /* avoid helices of length 1 */ char backtrack_type='F'; /* 'C' require (1,N) to be bonded; 'M' seq is part of s multi loop */ int *cut_points; int *strand; char * option_string(void) { static char options[100]; *options = '\0'; if (noGU) strcat(options, "-noGU "); if (no_closingGU) strcat(options, "-noCloseGU "); if (!tetra_loop) strcat(options, "-4 "); if (noLonelyPairs) strcat(options, "-noLP "); if (fold_constrained) strcat(options, "-C "); if (dangles!=1) sprintf(options+strlen(options), "-d%d ", dangles); if (temperature!=37.0) sprintf(options+strlen(options), "-T %f ", temperature); return options; }